PDB entry 7l0f

View 7l0f on RCSB PDB site
Description: Monobody 12VC3 Bound to HRAS(WT)
Class: signaling protein
Keywords: RAS GTPase, SIGNALING PROTEIN
Deposited on 2020-12-11, released 2021-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7l0fa_
  • Chain 'B':
    Compound: Monobody 12VC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7L0F (Start-96)
    Domains in SCOPe 2.08: d7l0fb_
  • Chain 'E':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7l0fe_
  • Chain 'F':
    Compound: Monobody 12VC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7L0F (Start-96)
    Domains in SCOPe 2.08: d7l0ff_
  • Chain 'G':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7l0fg_
  • Chain 'H':
    Compound: Monobody 12VC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7L0F (Start-96)
    Domains in SCOPe 2.08: d7l0fh_
  • Chain 'L':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7l0fl_
  • Chain 'M':
    Compound: Monobody 12VC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7L0F (Start-96)
    Domains in SCOPe 2.08: d7l0fm_
  • Heterogens: MG, GSP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7l0fA (A:)
smteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fA (A:)
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7l0fB (B:)
gsvssvptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgsksta
tisglkpgvdytitvyargyskqgpykpspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fB (B:)
svptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgskstatisg
lkpgvdytitvyargyskqgpykpspisinyrt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7l0fE (E:)
smteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fE (E:)
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7l0fF (F:)
gsvssvptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgsksta
tisglkpgvdytitvyargyskqgpykpspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fF (F:)
svptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgskstatisg
lkpgvdytitvyargyskqgpykpspisinyrt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >7l0fG (G:)
smteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fG (G:)
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7l0fH (H:)
gsvssvptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgsksta
tisglkpgvdytitvyargyskqgpykpspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fH (H:)
ssvptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgskstatis
glkpgvdytitvyargyskqgpykpspisinyrt

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7l0fL (L:)
smteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fL (L:)
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >7l0fM (M:)
gsvssvptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgsksta
tisglkpgvdytitvyargyskqgpykpspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >7l0fM (M:)
svptklevvaatptslliswdapavtvffyiiaygetghgvgafqafrvpgskstatisg
lkpgvdytitvyargyskqgpykpspisinyrt