PDB entry 7kwh

View 7kwh on RCSB PDB site
Description: Spermidine N-acetyltransferase SpeG K23-Y32 chimera from Vibrio cholerae and hSSAT
Class: transferase
Keywords: SpeG Enzyme Allosteric, TRANSFERASE
Deposited on 2020-12-01, released 2020-12-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwha_
  • Chain 'B':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhb_
  • Chain 'C':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhc_
  • Chain 'D':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (25-28)
    Domains in SCOPe 2.07: d7kwhd_
  • Chain 'E':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhe_
  • Chain 'F':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhf_
  • Chain 'G':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhg_
  • Chain 'H':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhh_
  • Chain 'I':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhi_
  • Chain 'J':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhj_
  • Chain 'K':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhk_
  • Chain 'L':
    Compound: Spermidine N(1)-acetyltransferase
    Species: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) [TaxId:243277]
    Gene: speG, VC_A0947
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9KL03
      • engineered mutation (22-28)
    Domains in SCOPe 2.07: d7kwhl_
  • Heterogens: PO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kwhA (A:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhA (A:)
sqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvved
aqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylh
vavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kwhB (B:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhB (B:)
sqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvved
aqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylh
vavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7kwhC (C:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhC (C:)
qltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvveda
qknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhv
avenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7kwhD (D:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhD (D:)
sqltlralergdlrfihnlaryeywfeepyesfdeleelynkhihdnaerrfvvedaqkn
liglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhvave
npkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >7kwhE (E:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhE (E:)
sqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvved
aqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylh
vavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7kwhF (F:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhF (F:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >7kwhG (G:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhG (G:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7kwhH (H:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhH (H:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >7kwhI (I:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhI (I:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >7kwhJ (J:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhJ (J:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >7kwhK (K:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhK (K:)
sqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvved
aqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylh
vavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >7kwhL (L:)
mnsqltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvv
edaqknliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiy
lhvavenpkavhlyeecgfveeghlveeffingryqdvkrmyilqskylnrse

    Sequence, based on observed residues (ATOM records): (download) 
    >7kwhL (L:)
ltlralergdlrfihnlnkelaryeywfeepyesfdeleelynkhihdnaerrfvvedaq
knliglvelieinyihrsaefqiiiapehqgkgfartlinraldysftilnlhkiylhva
venpkavhlyeecgfveeghlveeffingryqdvkrmyilqskyln