PDB entry 7kh8

View 7kh8 on RCSB PDB site
Description: Human LMPTP in complex with inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Protein Tyrosine Phosphatase, LMWPTP, Inhibitor, Complex, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2020-10-20, released 2021-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-26, with a file datestamp of 2021-05-21.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Low molecular weight phosphotyrosine protein phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: Acp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24666 (3-156)
      • expression tag (2)
    Domains in SCOPe 2.08: d7kh8a1, d7kh8a2
  • Chain 'B':
    Compound: Low molecular weight phosphotyrosine protein phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: Acp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24666 (3-156)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d7kh8b1, d7kh8b2
  • Heterogens: WE7, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kh8A (A:)
ghgatksvlfvclgnicrspiaeavfrklvtdqnisenwrvdsaatsgyeignppdyrgq
scmkrhgipmshvarqitkedfatfdyilcmdesnlrdlnrksnqvktckakiellgsyd
pqkqliiedpyygndsdfetvyqqcvrccraflekah

    Sequence, based on observed residues (ATOM records): (download) 
    >7kh8A (A:)
gatksvlfvclgnicrspiaeavfrklvtdqnisenwrvdsaatsgyeignppdyrgqsc
mkrhgipmshvarqitkedfatfdyilcmdesnlrdlnrksnqvktckakiellgsydpq
kqliiedpyygndsdfetvyqqcvrccraflekah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kh8B (B:)
ghgatksvlfvclgnicrspiaeavfrklvtdqnisenwrvdsaatsgyeignppdyrgq
scmkrhgipmshvarqitkedfatfdyilcmdesnlrdlnrksnqvktckakiellgsyd
pqkqliiedpyygndsdfetvyqqcvrccraflekah

    Sequence, based on observed residues (ATOM records): (download) 
    >7kh8B (B:)
ghgatksvlfvclgnicrspiaeavfrklvtdqnisenwrvdsaatsgyeignppdyrgq
scmkrhgipmshvarqitkedfatfdyilcmdesnlrdlnrksnqvckakiellgsydpq
kqliiedpyygndsdfetvyqqcvrccraflekah