PDB entry 7kc7

View 7kc7 on RCSB PDB site
Description: Biotin Carboxylase domain of Thermophilic 2-Oxoglutarate Carboxylase bound to ADP without Magnesium with disordered phosphate tail
Class: ligase
Keywords: biotin carboxylase, biotin-dependent carboxylase, pyruvate carboxylase, ATP-grasp, Aquificales, rTCA, dimer interface, bicarbonate, Sequence Determining Positions, structural waters, thermophile, carbon fixation, thermophilic protein, dimer, wet interface, LIGASE
Deposited on 2020-10-05, released 2021-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-oxoglutarate carboxylase small subunit
    Species: Hydrogenobacter thermophilus [TaxId:940]
    Gene: cfiB, HTH_1393, Hydth_1383
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3DJ42 (13-End)
      • conflict (182)
    Domains in SCOPe 2.08: d7kc7a1, d7kc7a2, d7kc7a3
  • Chain 'B':
    Compound: 2-oxoglutarate carboxylase small subunit
    Species: Hydrogenobacter thermophilus [TaxId:940]
    Gene: cfiB, HTH_1393, Hydth_1383
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3DJ42 (13-End)
      • conflict (182)
    Domains in SCOPe 2.08: d7kc7b1, d7kc7b2, d7kc7b3
  • Heterogens: ADP, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7kc7A (A:)
mhhhhhhlvprgsmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmade
aymigvnpldtylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwk
vielmgdkarskevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgi
risrneeelvrnyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerd
csiqrrnqklveiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfie
mntriqvehpvtemitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgf
apsigtieryyvpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsale
tyeisgvkttipllinimkdkdfrdgkfttryleehphvfdyaehrdkedfvafisavia
syhgl

    Sequence, based on observed residues (ATOM records): (download) 
    >7kc7A (A:)
mfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymigvnpldtyl
naerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkvielmgdkarske
vmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgirisrneeelvrny
enayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiqrrnqklvei
apsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntriqvehpvte
mitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsigtieryyvp
ggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyeisgvkttipl
linimkdkdfrdgkfttryleehphvfdyae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7kc7B (B:)
mhhhhhhlvprgsmfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmade
aymigvnpldtylnaerivdlalevgaeaihpgygflaenehfarlceekgitfigphwk
vielmgdkarskevmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgi
risrneeelvrnyenayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerd
csiqrrnqklveiapsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfie
mntriqvehpvtemitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgf
apsigtieryyvpggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsale
tyeisgvkttipllinimkdkdfrdgkfttryleehphvfdyaehrdkedfvafisavia
syhgl

    Sequence, based on observed residues (ATOM records): (download) 
    >7kc7B (B:)
mfkkvlvanrgeiacrvirackelgiqtvaiyneiestarhvkmadeaymigvnpldtyl
naerivdlalevgaeaihpgygflaenehfarlceekgitfigphwkvielmgdkarske
vmkragvptvpgsdgilkdveeakriakeigypvllkasaggggrgirisrneeelvrny
enayneavkafgrgdlllekyienpkhiefqvlgdkygnvihlgerdcsiqrrnqklvei
apsllltpeqreyygslvvkaakeigyysagtmefiadekgnlyfiemntriqvehpvte
mitgvdivkwqiriaagerlrysqedirfngysiecrinaedpkkgfapsigtieryyvp
ggfgirvehasskgyeitpyydsliaklivwaplwevavdrmrsaletyeisgvkttipl
linimkdkdfrdgkfttryleehphvfdyae