PDB entry 7c11

View 7c11 on RCSB PDB site
Description: Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain
Class: ligase
Keywords: Formate assimilation, Methylobacterium extorquens CM4, formate-tetrahydrofolate ligase, metal usage, LIGASE
Deposited on 2020-05-02, released 2020-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 2.82 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11a_
  • Chain 'B':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed):
    • Uniprot B7L0A5 (0-556)
      • expression tag (557)
    Domains in SCOPe 2.08: d7c11b1, d7c11b2
  • Chain 'C':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11c_
  • Chain 'D':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11d_
  • Chain 'M':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11m_
  • Chain 'N':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11n_
  • Chain 'O':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11o_
  • Chain 'P':
    Compound: Formate-tetrahydrofolate ligase
    Species: Methylorubrum extorquens (strain CM4 / NCIMB 13688) [TaxId:440085]
    Gene: fhs, Mchl_0447
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7c11p_
  • Heterogens: TLA, ACT, FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7c11A (A:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11A (A:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7c11B (B:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11B (B:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >7c11C (C:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11C (C:)
psdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvta
isptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeq
inlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqsl
ggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkat
gamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagf
gadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanle
rhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeala
qavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgyg
klpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpa
adtirldangqidglf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7c11D (D:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11D (D:)
psdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvta
isptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeq
inlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqsl
ggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkat
gamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagf
gadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanle
rhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeala
qavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgyg
klpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpa
adtirldangqidglf

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >7c11M (M:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11M (M:)
sdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvtai
sptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeqi
nlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqslg
gvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkatg
amtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagfg
adlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanler
hvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaealaq
avvklaekpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgygklpv
cmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpaadti
rldangqidglf

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >7c11N (N:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11N (N:)
psdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvta
isptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeq
inlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqsl
ggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkat
gamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagf
gadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanle
rhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeala
qavvklaegekpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgygk
lpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpaa
dtirldangqidglf

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >7c11O (O:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11O (O:)
psdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvta
isptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeq
inlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqsl
ggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkat
gamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagf
gadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanle
rhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeala
qavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgyg
klpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpa
adtirldangqidglf

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >7c11P (P:)
mpsdieiaraatlkpiaqvaeklgipdealhnygkhiakidhdfiaslegkpegklvlvt
aisptpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpme
qinlhftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqs
lggvangfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvka
tgamtvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteag
fgadlgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanl
erhvnnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaeal
aqavvklaegeqkpltfayetetkitdkikaiatklygaadiqieskaatklagfekdgy
gklpvcmaktqysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvp
aadtirldangqidglfaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >7c11P (P:)
psdieiaraatlkpiaqvlgipdealhnygkhiakidhdfiaslegkpegklvlvtaisp
tpagegkttttvglgdalnrigkravmclrepslgpcfgmkggaagggkaqvvpmeqinl
hftgdfhaitsahslaaalidnhiywanelnidvrrihwrrvvdmndralrainqslggv
angfpredgfditvasevmavfclaknladleerlgriviaetrdrkpvtladvkatgam
tvllkdalqpnlvqtlegnpalihggpfaniahgcnsviatrtglrladytvteagfgad
lgaekfidikcrqtglkpssvvivatiralkmhggvnkkdlqaenldalekgfanlerhv
nnvrsfglpvvvgvnhffqdtdaeharlkelcrdrlqveaitckhwaeggagaealaqav
vklaetfayetetkitdkikaiatklygaadiqieskaatklagfekdgygklpvcmakt
qysfstdptlmgapsghlvsvrdvrlsagagfvvvicgeimtmpglpkvpaadtirldan
gqidglf