PDB entry 6zqt

View 6zqt on RCSB PDB site
Description: Crystal structure of the RLIP76 Ral binding domain mutant (E427H/Q433L/K440R) in complex with RalB-GMPPNP
Class: protein binding
Keywords: RalB, RLIP76, Ral binding domain, coiled-coil, small GTPase, G protein, PROTEIN BINDING
Deposited on 2020-07-10, released 2020-11-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 1.51 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Ral-B
    Species: Homo sapiens [TaxId:9606]
    Gene: RALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11234
      • engineered mutation (71)
    Domains in SCOPe 2.07: d6zqta_
  • Chain 'B':
    Compound: Ras-related protein Ral-B
    Species: Homo sapiens [TaxId:9606]
    Gene: RALB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11234
      • engineered mutation (71)
    Domains in SCOPe 2.07: d6zqtb_
  • Chain 'C':
    Compound: RalA-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RALBP1, RLIP1, RLIP76
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15311
      • engineered mutation (23)
      • engineered mutation (39)
      • engineered mutation (45)
      • engineered mutation (52)
  • Chain 'D':
    Compound: RalA-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RALBP1, RLIP1, RLIP76
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15311 (5-End)
      • expression tag (0-4)
      • engineered mutation (23)
      • engineered mutation (39)
      • engineered mutation (45)
      • engineered mutation (52)
  • Heterogens: GNP, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zqtA (A:)
maankskgqsslalhkvimvgsggvgksaltlqfmydefvedyeptkadsyrkkvvldge
evqidildtagledyaairdnyfrsgegfllvfsitehesftataefreqilrvkaeedk
ipllvvgnksdleerrqvpveearskaeewgvqyvetsaktranvdkvffdlmreirtkk
msenk

    Sequence, based on observed residues (ATOM records): (download) 
    >6zqtA (A:)
slalhkvimvgsggvgksaltlqfmydefvedyeptkadsyrkkvvldgeevqidildta
gledyaairdnyfrsgegfllvfsitehesftataefreqilrvkaeedkipllvvgnks
dleerrqvpveearskaeewgvqyvetsaktranvdkvffdlmreirtkkmse

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zqtB (B:)
maankskgqsslalhkvimvgsggvgksaltlqfmydefvedyeptkadsyrkkvvldge
evqidildtagledyaairdnyfrsgegfllvfsitehesftataefreqilrvkaeedk
ipllvvgnksdleerrqvpveearskaeewgvqyvetsaktranvdkvffdlmreirtkk
msenk

    Sequence, based on observed residues (ATOM records): (download) 
    >6zqtB (B:)
alhkvimvgsggvgksaltlqfmydefvedyeptkadsyrkkvvldgeevqidildtagl
edyaairdnyfrsgegfllvfsitehesftataefreqilrvkaeedkipllvvgnksdl
eerrqvpveearskaeewgvqyvetsaktranvdkvffdlmreirtkkmse

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.