PDB entry 6ze8

View 6ze8 on RCSB PDB site
Description: Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound OATD-01
Class: hydrolase
Keywords: chitinase, chitin binding, HYDROLASE
Deposited on 2020-06-16, released 2020-11-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-06, with a file datestamp of 2021-01-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8a1, d6ze8a2
  • Chain 'B':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8b1, d6ze8b2
  • Chain 'C':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8c1, d6ze8c2
  • Chain 'D':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8d1, d6ze8d2
  • Chain 'E':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8e1, d6ze8e2
  • Chain 'F':
    Compound: chitotriosidase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CHIT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ze8f1, d6ze8f2
  • Heterogens: QGB, NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8A (A:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8B (B:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8C (C:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8D (D:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8E (E:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ze8F (F:)
aklvcyftnwaqyrqgearflpkdldpslcthliyafagmtnhqlsttewndetlyqefn
glkkmnpklktllaiggwnfgtqkftdmvatannrqtfvnsairflrkysfdgldldwey
pgsqgspavdkerfttlvqdlanafqqeaqtsgkerlllsaavpagqtyvdagyevdkia
qnldfvnlmaydfhgswekvtghnsplykrqeesgaaaslnvdaavqqwlqkgtpaskli
lgmptygrsftlasssdtrvgapatgsgtpgpftkeggmlayyevcswkgatkqriqdqk
vpyifrdnqwvgfddvesfktkvsylkqkglggamvwaldlddfagfscnqgrypliqtl
rqels