PDB entry 6xze

View 6xze on RCSB PDB site
Description: crystal structure of human carbonic anhydrase I in complex with 4-(3-(2-((2-fluorobenzyl)amino)ethyl)ureido) benzenesulfonamide
Class: lyase
Keywords: Inhibitor, carbon dioxide, carbonic anhydrase, LYASE
Deposited on 2020-02-04, released 2020-09-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-23, with a file datestamp of 2020-09-18.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6xzea_
  • Chain 'B':
    Compound: Carbonic anhydrase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6xzeb_
  • Heterogens: O4Z, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6xzeA (A:)
maspdwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakei
invghsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelh
vahwnsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnf
dpstllpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnav
pmqhnnrptqplkgrtvrasf

    Sequence, based on observed residues (ATOM records): (download) 
    >6xzeA (A:)
dwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakeiinvg
hsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelhvahw
nsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnfdpst
llpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnavpmqh
nnrptqplkgrtvrasf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6xzeB (B:)
maspdwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakei
invghsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelh
vahwnsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnf
dpstllpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnav
pmqhnnrptqplkgrtvrasf

    Sequence, based on observed residues (ATOM records): (download) 
    >6xzeB (B:)
dwgyddkngpeqwsklypiangnnqspvdiktsetkhdtslkpisvsynpatakeiinvg
hsfhvnfedndnrsvlkggpfsdsyrlfqfhfhwgstnehgsehtvdgvkysaelhvahw
nsakysslaeaaskadglavigvlmkvgeanpklqkvldalqaiktkgkrapftnfdpst
llpssldfwtypgslthpplyesvtwiickesisvsseqlaqfrsllsnvegdnavpmqh
nnrptqplkgrtvrasf