PDB entry 6wkb

View 6wkb on RCSB PDB site
Description: Human S-adenosylmethionine synthetase co-crystallized with UppNHp and Met
Class: transferase
Keywords: S-adenosylmethionine synthetase, TRANSFERASE
Deposited on 2020-04-15, released 2021-04-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wkba1, d6wkba2, d6wkba3
  • Chain 'B':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6wkbb1, d6wkbb2, d6wkbb3
  • Heterogens: U4P, MED, EDO, MET, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6wkbA (A:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >6wkbA (A:)
egtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsr
aavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigagd
qglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrga
vlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfvigg
pqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrv
lvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrt
aayghfgrdsfpwevpkklky

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6wkbB (B:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >6wkbB (B:)
gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigagdq
glmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgav
lpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggp
qgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvl
vqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrta
ayghfgrdsfpwevpkklky