PDB entry 6t4k
View 6t4k on RCSB PDB site
Description: ROR(gamma)t ligand binding domain in complex with desmosterol and allosteric ligand MRL871
Class: gene regulation
Keywords: Nuclear Receptor, Allosteric, Inverse Agonist, Inhibitor, GENE REGULATION
Deposited on
2019-10-14, released
2020-11-18
The last revision prior to the SCOPe 2.07 freeze date was dated
2020-11-18, with a file datestamp of
2020-11-13.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Nuclear receptor ROR-gamma
Species: Homo sapiens [TaxId:9606]
Gene: RORC, NR1F3, RORG, RZRG
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6t4ka_ - Heterogens: MHQ, 4F1, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6t4kA (A:)
gsshhhhhhssglvprgshmaslteiehlvqsvcksyretcqlrledllrqrsnifsree
vtgyqrksmwemwercahhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvr
mcraynadnrtvffegkyggmelfralgcselissifdfshslsalhfsedeialytalv
linahrpglqekrkveqlqynlelafhhhlhkthrqsilaklppkgklrslcsqhverlq
ifqhlhpivvqaafpplykelfs
Sequence, based on observed residues (ATOM records): (download)
>6t4kA (A:)
lteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahhlte
aiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkyggme
lfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlqynl
elafhhhlhkthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpplykelf
s