PDB entry 6sqn

View 6sqn on RCSB PDB site
Description: Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA
Class: RNA binding protein
Keywords: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A, U1A, RNA hairpin, co-crystallization, RNA BINDING PROTEIN
Deposited on 2019-09-04, released 2020-05-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-13, with a file datestamp of 2020-05-08.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: U1 small nuclear ribonucleoprotein A
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09012 (0-End)
      • engineered mutation (29)
      • engineered mutation (34)
      • engineered mutation (54)
    Domains in SCOPe 2.07: d6sqna_
  • Chain 'B':
    Compound: U1 small nuclear ribonucleoprotein A
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09012 (0-End)
      • engineered mutation (29)
      • engineered mutation (34)
      • engineered mutation (54)
    Domains in SCOPe 2.07: d6sqnb_
  • Chain 'C':
    Compound: U1 small nuclear ribonucleoprotein A
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09012
      • engineered mutation (29)
      • engineered mutation (34)
      • engineered mutation (54)
    Domains in SCOPe 2.07: d6sqnc_
  • Chain 'X':
    Compound: RNA hairpin
    Species: Homo sapiens [TaxId:9606]
  • Chain 'Y':
    Compound: RNA hairpin
    Species: Homo sapiens [TaxId:9606]
  • Chain 'Z':
    Compound: RNA hairpin
    Species: Homo sapiens [TaxId:9606]
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sqnA (A:)
avpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifke
vssatnalrsmqgfpfydkpmriqyaktdsdiiakmk

    Sequence, based on observed residues (ATOM records): (download) 
    >6sqnA (A:)
avpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifke
vssatnalrsmqgfpfydkpmriqyaktdsdiiakm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6sqnB (B:)
avpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifke
vssatnalrsmqgfpfydkpmriqyaktdsdiiakmk

    Sequence, based on observed residues (ATOM records): (download) 
    >6sqnB (B:)
avpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifke
vssatnalrsmqgfpfydkpmriqyaktdsdiiakm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6sqnC (C:)
avpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifke
vssatnalrsmqgfpfydkpmriqyaktdsdiiakmk

    Sequence, based on observed residues (ATOM records): (download) 
    >6sqnC (C:)
vpetrpnhtiyinnlnekikkdelkkslhaifsrfgqildilvsrslkmrgqawvifkev
ssatnalrsmqgfpfydkpmriqyaktdsdiiakm

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.

  • Chain 'Z':
    No sequence available.