PDB entry 6s03

View 6s03 on RCSB PDB site
Description: Carbonic Anhydrase CAIX mimic in complex with inhibitor I39LT379
Class: lyase
Keywords: carbonic anhydrase, inhibitor, LYASE
Deposited on 2019-06-13, released 2020-06-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-06-03, with a file datestamp of 2020-05-29.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (Start-259)
      • conflict (64)
      • conflict (66)
      • conflict (68)
      • conflict (90)
      • conflict (129)
      • conflict (168)
      • conflict (202)
      • conflict (222)
    Domains in SCOPe 2.07: d6s03a_
  • Heterogens: KPW, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6s03A (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdp
rgllpesldywtypgslttpplaecvtwivlkepisvsseqvvkfrklnfngegepeelm
vdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >6s03A (A:)
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdprgl
lpesldywtypgslttpplaecvtwivlkepisvsseqvvkfrklnfngegepeelmvdn
wrpaqplknrqikasfk