PDB entry 6ru0

View 6ru0 on RCSB PDB site
Description: Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
Class: lyase
Keywords: unnatural amino acids, phenylalanine-4'-azobenzene (AzoF), o-nitropiperonyl-O-tyrosine (NPY), lyase
Deposited on 2019-05-27, released 2020-05-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Imidazole glycerol phosphate synthase subunit hisF
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisF, TM_1036
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • conflict (54)
    Domains in SCOPe 2.07: d6ru0a_
  • Chain 'B':
    Compound: imidazole glycerol phosphate synthase subunit hish
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisH, TM_1038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ru0b_
  • Chain 'C':
    Compound: Imidazole glycerol phosphate synthase subunit hisF
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisF, TM_1036
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • conflict (54)
    Domains in SCOPe 2.07: d6ru0c_
  • Chain 'D':
    Compound: imidazole glycerol phosphate synthase subunit hish
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisH, TM_1038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ru0d_
  • Chain 'E':
    Compound: Imidazole glycerol phosphate synthase subunit hisF
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisF, TM_1036
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • conflict (54)
    Domains in SCOPe 2.07: d6ru0e_
  • Chain 'F':
    Compound: imidazole glycerol phosphate synthase subunit hish
    Species: Thermotoga maritima [TaxId:2336]
    Gene: hisH, TM_1038
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ru0f_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ru0A (A:)
mlakriiacldvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditafvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ru0B (B:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6ru0B (B:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ru0C (C:)
mlakriiacldvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditafvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ru0D (D:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6ru0D (D:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsr

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ru0E (E:)
mlakriiacldvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditafvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6ru0F (F:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6ru0F (F:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecsls