PDB entry 6qju

View 6qju on RCSB PDB site
Description: Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with 3-bromo-1H-indazol-5-amine
Class: signaling protein
Keywords: Bromodomain, Complex, Inhibitor, Ligand, Halogen bonding, XB, HEFLib, halogen-enriched fragment library, SIGNALING PROTEIN
Deposited on 2019-01-25, released 2020-02-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD3, KIAA0043, RING3L
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qjua_
  • Chain 'B':
    Compound: Bromodomain-containing protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD3, KIAA0043, RING3L
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qjub_
  • Heterogens: J58, EDO, SCN, DMS, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qjuA (A:)
smpevsnpskpgrktnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpm
dmgtikkrlennyywsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmp
qee

    Sequence, based on observed residues (ATOM records): (download) 
    >6qjuA (A:)
rktnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpmdmgtikkrlenn
yywsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmpqee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qjuB (B:)
smpevsnpskpgrktnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpm
dmgtikkrlennyywsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmp
qee

    Sequence, based on observed residues (ATOM records): (download) 
    >6qjuB (B:)
pevsnpskpgrktnqlqymqnvvvktlwkhqfawpfyqpvdaiklnlpdyhkiiknpmdm
gtikkrlennyywsasecmqdfntmftncyiynkptddivlmaqalekiflqkvaqmpqe