PDB entry 6qgq

View 6qgq on RCSB PDB site
Description: Crystal structure of APT1 C2S mutant bound to palmitic acid.
Class: hydrolase
Keywords: acyl-protein thioesterase, palmitic acid, Depalmitoylation, HYDROLASE
Deposited on 2019-01-12, released 2020-02-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qgqa_
  • Chain 'B':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75608 (Start-232)
      • expression tag (233)
    Domains in SCOPe 2.07: d6qgqb1, d6qgqb2
  • Chain 'C':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qgqc_
  • Chain 'D':
    Compound: Acyl-protein thioesterase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: LYPLA1, APT1, LPL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6qgqd_
  • Heterogens: GOL, PLM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6qgqA (A:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgqA (A:)
tplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnv
ampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalsly
talttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltve
klktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6qgqB (B:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppida

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgqB (B:)
plpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnva
mpswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalslyt
alttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltvek
lktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppida

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6qgqC (C:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgqC (C:)
plpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnva
mpswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalslyt
alttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltvek
lktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6qgqD (D:)
gsrmsgnnmstplpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphap
vrpvtlnmnvampswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilgg
fsqggalslytalttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplv
plmfgsltveklktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppid

    Sequence, based on observed residues (ATOM records): (download) 
    >6qgqD (D:)
plpaivpaarkataaviflhglgdtghgwaeafagirsshikyicphapvrpvtlnmnva
mpswfdiiglspdsqedesgikqaaenikalidqevkngipsnriilggfsqggalslyt
alttqqklagvtalscwlplrasfpqgpigganrdisilqchgdcdplvplmfgsltvek
lktlvnpanvtfktyegmmhsscqqemmdvkqfidkllppi