PDB entry 6pg8

View 6pg8 on RCSB PDB site
Description: WDR5delta23 bound to (2-(3-phenylpropyl)-1H-imidazol-4-yl)methanol
Class: PROTEIN BINDING/Inhibitor
Keywords: Inhibitor, Scaffolding Protein, B-propellor, Chromatin regulator, PROTEIN BINDING, PROTEIN BINDING-Inhibitor complex
Deposited on 2019-06-24, released 2019-12-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6pg8a_
  • Chain 'B':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61964 (1-313)
      • expression tag (0)
    Domains in SCOPe 2.07: d6pg8b1, d6pg8b2
  • Chain 'C':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6pg8c_
  • Chain 'D':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6pg8d_
  • Heterogens: OGY, CL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6pg8A (A:)
gsatqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfe
ktisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpq
snlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdt
asgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghkneky
cifanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaa
lendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >6pg8A (A:)
vkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktln
ppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtggkwi
vsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklwksdc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6pg8B (B:)
gsatqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfe
ktisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpq
snlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdt
asgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghkneky
cifanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaa
lendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >6pg8B (B:)
gsatqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfe
ktisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpq
snlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdt
asgqclktlnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifa
nfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalend
ktiklwksdc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6pg8C (C:)
gsatqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfe
ktisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpq
snlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdt
asgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghkneky
cifanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaa
lendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >6pg8C (C:)
vkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6pg8D (D:)
gsatqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfe
ktisghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpq
snlivsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdt
asgqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghkneky
cifanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaa
lendktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >6pg8D (D:)
vkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc