PDB entry 6p9v
View 6p9v on RCSB PDB site
Description: Crystal Structure of hMAT Mutant K289L
Class: transferase
Keywords: Adenosyl transferase, AdoMet synthase, Natural Product Enzyme, TRANSFERASE
Deposited on
2019-06-10, released
2020-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated
2020-04-22, with a file datestamp of
2020-04-17.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: S-adenosylmethionine synthase isoform type-2
Species: Homo sapiens [TaxId:9606]
Gene: MAT2A, AMS2, MATA2
Database cross-references and differences (RAF-indexed):
- Uniprot P31153 (Start-414)
- engineered mutation (308)
Domains in SCOPe 2.07: d6p9va1, d6p9va2, d6p9va3 - Heterogens: ADN, MG, POP, K, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6p9vA (A:)
mgsshhhhhhssglvprgshmngqlngfheafieegtflftsesvgeghpdkicdqisda
vldahlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfd
yktcnvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahkl
naklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrd
alkekvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahggg
afsgkdytlvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqk
serelleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklky
Sequence, based on observed residues (ATOM records): (download)
>6p9vA (A:)
gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigagdq
glmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgav
lpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggp
qgdagltgrkiivdtyggwgahgggafsgkdytlvdrsaayaarwvakslvkgglcrrvl
vqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrta
ayghfgrdsfpwevpkklky