PDB entry 6p9v

View 6p9v on RCSB PDB site
Description: Crystal Structure of hMAT Mutant K289L
Class: transferase
Keywords: Adenosyl transferase, AdoMet synthase, Natural Product Enzyme, TRANSFERASE
Deposited on 2019-06-10, released 2020-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31153 (Start-414)
      • engineered mutation (308)
    Domains in SCOPe 2.07: d6p9va1, d6p9va2, d6p9va3
  • Heterogens: ADN, MG, POP, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6p9vA (A:)
    mgsshhhhhhssglvprgshmngqlngfheafieegtflftsesvgeghpdkicdqisda
    vldahlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfd
    yktcnvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahkl
    naklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrd
    alkekvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahggg
    afsgkdytlvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqk
    serelleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklky
    

    Sequence, based on observed residues (ATOM records): (download)
    >6p9vA (A:)
    gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
    avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdiaqgvhldrneedigagdq
    glmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgav
    lpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggp
    qgdagltgrkiivdtyggwgahgggafsgkdytlvdrsaayaarwvakslvkgglcrrvl
    vqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrta
    ayghfgrdsfpwevpkklky