PDB entry 6oql

View 6oql on RCSB PDB site
Description: CDK6 in complex with Cpd13 (R)-5-fluoro-4-(4-methyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a]azepin-3-yl)-N-(5-(4-methylpiperazin-1-yl)pyridin-2-yl)pyrimidin-2-amine
Class: TRANSFERASE/TRANSFERASE inhibitor
Keywords: kinase, TRANSFERASE, TRANSFERASE-TRANSFERASE inhibitor complex
Deposited on 2019-04-26, released 2020-07-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-24.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 6
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK6, CDKN6
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6oqla_
  • Heterogens: N1A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6oqlA (A:)
qqyecvaeigegaygkvfkardlknggrfvalkrvrvqtgeegmplstirevavlrhlet
fehpnvvrlfdvctvsrtdretkltlvfehvdqdlttyldkvpepgvptetikdmmfqll
rgldflhshrvvhrdlkpqnilvtssgqikladfglariysfqmaltsvvvtlwyrapev
llqssyatpvdlwsvgcifaemfrrkplfrgssdvdqlgkildviglpgeedwprdvalp
rqafhsksaqpiekfvtdidelgkdlllkcltfnpakrisaysalshpyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6oqlA (A:)
qqyecvaeigegaygkvfkardlknggrfvalkrvrvplstirevavlrhletfehpnvv
rlfdvctkltlvfehvdqdlttyldkvpepgvptetikdmmfqllrgldflhshrvvhrd
lkpqnilvtssgqikladfglavtlwyrapevllqssyatpvdlwsvgcifaemfrrkpl
frgssdvdqlgkildviglpgeedwprdvalprqafhsksaqpiekfvtdidelgkdlll
kcltfnpakrisaysalshpyfq