PDB entry 6ojh

View 6ojh on RCSB PDB site
Description: Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
Class: ligase
Keywords: ATP grasp, carboxylase, inhibitor, ligase
Deposited on 2019-04-11, released 2020-02-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: biotin carboxylase
    Species: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [TaxId:71421]
    Gene: accC, HI_0972
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ojha1, d6ojha2, d6ojha3
  • Heterogens: MV4, CA, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ojhA (A:)
mgsshhhhhhssglvprgshmlekvvianrgeialrilrackelgiktvavhstadrdlk
hvlladeticigpapsaksylnipaiiaaaevtgadaihpgygflsenadfaeqversgf
tfigptadvirlmgdkvsaikamkkagvpcvpgsdgpvsndiaknkeiakrigypiiika
sgggggrgmrvvrsedaleesiamtkaeakaafnndmvymekylenprhveiqvladthg
navylaerdcsmqrrhqkvveeapapgiteevrrdigsrcanacveigyrgagtfeflye
ngefyfiemntriqvehpvtemitgvdlvkeqlriaaglpisfkqedikvkghamecrin
aedpktflpspgkvnhlhspgglgvrwdshvyggytvpphydsmiaklitygdtrevair
rmqnalsetiidgiktniplheliledenfqkggtnihylekklgmne

    Sequence, based on observed residues (ATOM records): (download) 
    >6ojhA (A:)
mlekvvianrgeialrilrackelgiktvavhstadrdlkhvlladeticigpapsaksy
lnipaiiaaaevtgadaihpgygflsenadfaeqversgftfigptadvirlmgdkvsai
kamkkagvpcvpgsdgpvsndiaknkeiakrigypiiikasgggggrgmrvvrsedalee
siamtkaeakaafnndmvymekylenprhveiqvladthgnavylaerdcsmqrrhqkvv
eeapapgiteevrrdigsrcanacveigyrgagtfeflyengefyfiemntriqvehpvt
emitgvdlvkeqlriaaglpisfkqedikvkghamecrinaedpktflpspgkvnhlhsp
gglgvrwdshvyggytvpphydsmiaklitygdtrevairrmqnalsetiidgiktnipl
heliledenfqkggtnihylekklg