PDB entry 6oda

View 6oda on RCSB PDB site
Description: Crystal structure of HDAC8 in complex with compound 2
Class: hydrolase
Keywords: histone deacetylase, HDAC8, hydroxamic acid, HYDROLASE
Deposited on 2019-03-26, released 2020-04-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-01, with a file datestamp of 2020-03-27.
Experiment type: XRAY
Resolution: 2.88 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC8, HDACL1, CDA07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6odaa_
  • Chain 'B':
    Compound: Histone deacetylase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC8, HDACL1, CDA07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6odab_
  • Chain 'C':
    Compound: Histone deacetylase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC8, HDACL1, CDA07
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6odac_
  • Heterogens: C7, ZN, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6odaA (A:)
mhhhhhhssgvdlgtenlyfqsnameepeepadsgqslvpvyiyspeyvsmcdslakipk
rasmvhslieayalhkqmrivkpkvasmeematfhtdaylqhlqkvsqegdddhpdsiey
glgydcpategifdyaaaiggatitaaqclidgmckvainwsggwhhakkdeasgfcyln
davlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkfspgffpgtgdvsd
vglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlqlgadtiagdpmcs
fnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvilgktlsseipdhef
ftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvviegrgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6odaA (A:)
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6odaB (B:)
mhhhhhhssgvdlgtenlyfqsnameepeepadsgqslvpvyiyspeyvsmcdslakipk
rasmvhslieayalhkqmrivkpkvasmeematfhtdaylqhlqkvsqegdddhpdsiey
glgydcpategifdyaaaiggatitaaqclidgmckvainwsggwhhakkdeasgfcyln
davlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkfspgffpgtgdvsd
vglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlqlgadtiagdpmcs
fnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvilgktlsseipdhef
ftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvviegrgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6odaB (B:)
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6odaC (C:)
mhhhhhhssgvdlgtenlyfqsnameepeepadsgqslvpvyiyspeyvsmcdslakipk
rasmvhslieayalhkqmrivkpkvasmeematfhtdaylqhlqkvsqegdddhpdsiey
glgydcpategifdyaaaiggatitaaqclidgmckvainwsggwhhakkdeasgfcyln
davlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkfspgffpgtgdvsd
vglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlqlgadtiagdpmcs
fnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvilgktlsseipdhef
ftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvviegrgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6odaC (C:)
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqeyglgydcpategifdyaaaiggatitaaqclidgmckvainwsggwhh
akkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkf
spgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlq
lgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvil
gktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhv