PDB entry 6oan

View 6oan on RCSB PDB site
Description: Structure of DBP in complex with human neutralizing antibody 053054
Class: cell invasion
Keywords: Plasmodium, vivax, Duffy Binding Protein, DBP, PvDBP, antibody, neutralizing, inhibition, malaria, invasion, blocking, vaccine, structural vaccinology, CELL INVASION
Deposited on 2019-03-18, released 2019-06-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Duffy binding surface protein region II
    Species: Plasmodium vivax [TaxId:5855]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6oana_
  • Chain 'B':
    Compound: Antibody 053054 single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6OAN
    Domains in SCOPe 2.07: d6oanb1, d6oanb2
  • Chain 'C':
    Compound: Duffy binding surface protein region II
    Species: Plasmodium vivax [TaxId:5855]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6oanc_
  • Chain 'D':
    Compound: Antibody 053054 single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6OAN
    Domains in SCOPe 2.07: d6oand1, d6oand2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6oanA (A:)
ntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfrkl
ylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvven
nlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiy
rwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqw
dvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcsve
eakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >6oanA (A:)
ncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvditfrklylkrkliydaaveg
dlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsifgtdekaqq
rrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiyrwirewgrdyvsel
ptevqklkecqnacksydqwitrkknqwdvlsnkfisvknaagivtpydilkqeldefne
vafeneinkrdgay

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6oanB (B:)
mvhsqvqlqesgpglvkpsqtlsltcnvsgdsinsgdyywiwirqppgkglewigniyys
gtayynpslktrliisidtstnqfslkvtsvtaadtaiyycarasttvvspwldpwgqgt
lvtvssaggggsggggsggggssvtsyeltqpssvavapgqtaripcggdnieskgvhwy
qqkpgqapvlvvyddhdrpsgiperfsgsnsgntatltvsrveagdeadyycqvwdtsse
hpvfgggtkltvlgqpkaapsvtlfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6oanB (B:)
vqlqesgpglvkpsqtlsltcnvsgdsinsgdyywiwirqppgkglewigniyysgtayy
npslktrliisidtstnqfslkvtsvtaadtaiyycarasttvvspwldpwgqgtlvtvs
yeltqpssvavapgqtaripcggdnieskgvhwyqqkpgqapvlvvyddhdrpsgiperf
sgsnsgntatltvsrveagdeadyycqvwdtssehpvfgggtkltvlgq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6oanC (C:)
ntvmkncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvnntdtnfhrditfrkl
ylkrkliydaavegdlllklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvven
nlrsifgtdekaqqrrkqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiy
rwirewgrdyvselptevqklkekcdgkinytdkkvckvppcqnacksydqwitrkknqw
dvlsnkfisvknaekvqtagivtpydilkqeldefnevafeneinkrdgayielcvcsve
eakkntqevvtnvdn

    Sequence, based on observed residues (ATOM records): (download) 
    >6oanC (C:)
ncnykrkrrerdwdcntkkdvcipdrryqlcmkeltnlvtfrklylkrkliydaavegdl
llklnnyrynkdfckdirwslgdfgdiimgtdmegigyskvvennlrsifgtdekaqqrr
kqwwneskaqiwtammysvkkrlkgnfiwicklnvavniepqiyrwirewgrdyvselpt
evqkcqnacksydqwitrkknqwdvlsnkfisvknatagivtpydilkqelfnevafene
inkrdgay

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6oanD (D:)
mvhsqvqlqesgpglvkpsqtlsltcnvsgdsinsgdyywiwirqppgkglewigniyys
gtayynpslktrliisidtstnqfslkvtsvtaadtaiyycarasttvvspwldpwgqgt
lvtvssaggggsggggsggggssvtsyeltqpssvavapgqtaripcggdnieskgvhwy
qqkpgqapvlvvyddhdrpsgiperfsgsnsgntatltvsrveagdeadyycqvwdtsse
hpvfgggtkltvlgqpkaapsvtlfp

    Sequence, based on observed residues (ATOM records): (download) 
    >6oanD (D:)
vqlqesgpglvkpsqtlsltcnvsgdsinsgdyywiwirqppgkglewigniyysgtayy
npslktrliisidtstnqfslkvtsvtaadtaiyycarasttvvspwldpwgqgtlvtvs
syeltqpssvavapgqtaripcggdnieskgvhwyqqkpgqapvlvvyddhdrpsgiper
fsgsnsgntatltvsrveagdeadyycqvwdtssehpvfgggtkltvl