SCOPe 2.07: Structural Classification of Proteins

PDB entry 6o4i

View 6o4i on RCSB PDB site
Description: Structure of ALDH7A1 mutant E399D complexed with alpha-aminoadipate
Class: oxidoreductase
Keywords: aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism
Deposited on 2019-02-28, released 2019-11-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ia_
Chain 'B':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ib_
Chain 'C':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ic_
Chain 'D':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4id_
Chain 'E':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ie_
Chain 'F':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4if_
Chain 'G':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ig_
Chain 'H':
Compound: Alpha-aminoadipic semialdehyde dehydrogenase
Species: Homo sapiens [TaxId:9606]
Gene: ALDH7A1, ATQ1
Database cross-references and differences (RAF-indexed):
- Uniprot P49419 (Start-512)
  - engineered mutation (400)
Domains in SCOPe 2.07: d6o4ih_
Heterogens: UN1, EDO, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6o4iA (A:)
ghmstllinqpqyawlkelglreenegvyngswggrgevittycpannepiarvrqasva
dyeetvkkareawkiwadipapkrgeivrqigdalrekiqvlgslvslemgkilvegvge
vqeyvdicdyavglsrmiggpilpsersghalieqwnpvglvgiitafnfpvavygwnna
iamicgnvclwkgapttslisvavtkiiakvlednklpgaicsltcggadigtamakder
vnllsftgstqvgkqvglmvqerfgrsllelggnnaiiafedadlslvvpsalfaavgta
gqrcttarrlfihesihdevvnrlkkayaqirvgnpwdpnvlygplhtkqavsmflgave
eakkeggtvvyggkvmdrpgnyveptivtglghdasiahtdtfapilyvfkfkneeevfa
wnnevkqglsssiftkdlgrifrwlgpkgsdcgivnvniptsgaeiggafggekhtgggr
esgsdawkqymrrstctinyskdlplaqgikfq