PDB entry 6ml8

View 6ml8 on RCSB PDB site
Description: Crystal structure of hemagglutinin from H1N1 Influenza A virus A/Denver/57 bound to the C05 antibody
Class: viral protein
Keywords: NIAID, structural genomics, influenza virus, vaccine development, broadly neutralizing antibody, strain-specific neutralization, influenzavirus, Seattle Structural Genomics Center for Infectious Disease, SSGCID, VIRAL PROTEIN
Deposited on 2018-09-27, released 2018-10-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.92 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:385583]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ml8a_
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus (A/Denver/1957(H1N1)) [TaxId:385583]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ml8b_
  • Chain 'H':
    Compound: C05 antibody Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ML8 (0-End)
    Domains in SCOPe 2.08: d6ml8h_
  • Chain 'L':
    Compound: C05 antibody Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ML8 (0-End)
    Domains in SCOPe 2.08: d6ml8l1, d6ml8l2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ml8A (A:)
fagsdticigyhannstdtvdtvleknvtvthsvnlledshngklcrlkgkaplqlgncn
iagwvlgnpecesllsnrswsyiaetpnsengtcypgdfadyeelreqlssvssferfei
fpkerswpnhttrgvtaacpharkssfyknlvwlteangsypnlsrsyvnnqekevlvlw
gvhhpsnieeqralyrkdnayvsvvssnynrrftpeiakrpkvrdqsgrmnyywtllepg
dtiifeatgnliapwyafalsrgpgsgiitsnapldecdtkcqtpqgainsslpfqnihp
vtigecpkyvrstklrmvtglrnipsvqsr

    Sequence, based on observed residues (ATOM records): (download) 
    >6ml8A (A:)
ticigyhannstdtvdtvleknvtvthsvnlledshngklcrlkgkaplqlgncniagwv
lgnpecesllsnrswsyiaetpnsengtcypgdfadyeelreqlssvssferfeifpker
swpnhttrgvtaacpharkssfyknlvwlteangsypnlsrsyvnnqekevlvlwgvhhp
snieeqralyrkdnayvsvvssnynrrftpeiakrpkvrdqsgrmnyywtllepgdtiif
eatgnliapwyafalsrgpgsgiitsnapldecdtkcqtpqgainsslpfqnihpvtige
cpkyvrstklrmvtglrnips

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ml8B (B:)
glfgaiagfieggwtgmmdgwygyhhqneqgsgyaadqkstqnaingitnkvnsviekmn
tqftavgkefnklekrmenlnkkvddgfmdiwtynaellvllenertldfhdsnvknlye
kvknqlrnnakelgngcfefyhkcdnecmesvkngtydypkysee

    Sequence, based on observed residues (ATOM records): (download) 
    >6ml8B (B:)
fgaiagfieggwtgmmdgwygyhhqneqgsgyaadqkstqnaingitnkvnsviekmntq
ftavgkefnklekrmenlnkkvddgfmdiwtynaellvllenertldfhdsnvknlyekv
knqlrnnakelgngcfefyhkcdnecmesvkngtydy

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6ml8H (H:)
evqlqesggglvqpgeslrlscvgsgssfgestlsyyavswvrqapgkglewlsiinagg
gdidyadsvegrftisrdnsketlylqmtnlrvedtgvyycakhmsmqqvvsagweradl
vgdafdvwgqgtmvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswn
sgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepks
chhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ml8H (H:)
evqlqesggglvqpgeslrlscvgsgssfgestlsyyavswvrqapgkglewlsiinagg
gdidyadsvegrftisrdnsketlylqmtnlrvedtgvyycakhmsmqqvvsagweradl
vgdafdvwgqgtmvtvssastkgpsvfplaptaalgclvkdyfpepvtvswnsgaltsgv
htfpavlqssglyslssvvtvpsssltyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6ml8L (L:)
diqltqspsslsasvgdrvtltcqasqdirkflnwyqqkpgkgpklliydasnlqrgvps
rfsgggsgtdftliisslqpedvgtyycqqydglpftfgggtkvvikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6ml8L (L:)
diqltqspsslsasvgdrvtltcqasqdirkflnwyqqkpgkgpklliydasnlqrgvps
rfsgggsgtdftliisslqpedvgtyycqqydglpftfgggtkvvikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg