PDB entry 6mkk

View 6mkk on RCSB PDB site
Description: Crystallographic solvent mapping analysis of DMSO/Mg bound to APE1
Class: lyase
Keywords: Apurinic/apyrimidinic endonuclease, DNA repair, abasic site, solvent mapping, LYASE
Deposited on 2018-09-25, released 2019-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 1.44 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA-(apurinic or apyrimidinic site) lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: APEX1, APE, APE1, APEX, APX, HAP1, REF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27695 (6-284)
      • expression tag (3-5)
      • conflict (104)
    Domains in SCOPe 2.07: d6mkka1, d6mkka2
  • Heterogens: MG, DMS, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6mkkA (A:)
gshmasegpalyedppdqktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilc
lqetkcsenklpaelqelpglshqywsapsdkegysgvgllsrqaplkvsygigdeehdq
egrvivaefdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnv
aheeidlrnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmna
rsknvgwrldyfllshsllpalcdskirskalgsdhcpitlylal

    Sequence, based on observed residues (ATOM records): (download) 
    >6mkkA (A:)
masegpalyedppdqktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilclqe
tkcsenklpaelqelpglshqywsapsdkegysgvgllsrqaplkvsygigdeehdqegr
vivaefdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvahe
eidlrnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsk
nvgwrldyfllshsllpalcdskirskalgsdhcpitlylal