PDB entry 6mak

View 6mak on RCSB PDB site
Description: HBO1 is required for the maintenance of leukaemia stem cells
Class: antitumor protein/transferase
Keywords: MYST domain, cancer inhibitor, ANTITUMOR PROTEIN, antitumor protein-transferase complex
Deposited on 2018-08-27, released 2019-12-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 2.13 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT7
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT7, HBO1, HBOa, MYST2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6maka_
  • Chain 'B':
    Compound: BRD1 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, ACO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6makA (A:)
mgsmiktiafgryeldtwyhspypeeyarlgrlymcefclkymksqtilrrhmakcvwkh
ppgdeiyrkgsisvfevdgkknkiycqnlcllaklfldhktlyydvepflfyvmteadnt
gchligyfskeknsflnynvsciltmpqymrqgygkmlidfsyllskveekvgsperpls
dlglisyrsywkevllrylhnfqgkeisikeisqetavnpvdivstlqalqmlkywkgkh
lvlkrqdlidewiakeakrsnsnktmdpsclkwtppkas

    Sequence, based on observed residues (ATOM records): (download) 
    >6makA (A:)
miktiafgryeldtwyhspypeeyarlgrlymcefclkymksqtilrrhmakcvwkhppg
deiyrkgsisvfevdgkknkiycqnlcllaklfldhktlyydvepflfyvmteadntgch
ligyfskeknsflnynvsciltmpqymrqgygkmlidfsyllskveekvgsperplsdlg
lisyrsywkevllrylhnfqgkeisikeisqetavnpvdivstlqalqmlkywkgkhlvl
krqdlidewiakeakrsnsnktmdpsclkwtp

  • Chain 'B':
    No sequence available.