PDB entry 6k12

View 6k12 on RCSB PDB site
Description: Babesia microti lactate dehydrogenase apo form (BmLDH)
Class: oxidoreductase
Keywords: lactate dehydrogenase, inhibitor, OXIDOREDUCTASE
Deposited on 2019-05-09, released 2019-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-29, with a file datestamp of 2020-04-24.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6k12a1, d6k12a2
  • Chain 'B':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6k12b1, d6k12b2
  • Chain 'C':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6k12c1, d6k12c2
  • Chain 'D':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6k12d1, d6k12d2
  • Chain 'E':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: l-lactate dehydrogenase
    Species: Babesia microti (strain RI) [TaxId:1133968]
    Gene: BMR1_01G00020
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6k12f1, d6k12f2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6k12A (A:)
mhslkeeflirltnedlnasnkitvigvgavgmacafsilnkeladelvlidvvedklkg
emmdlqqgslflktpniiagkdyeltansklvvvtagarqqegesrlnlvqrnvnifkfi
ipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnldsarfrylvsemigi
hpsnfhgcilgehgdssvpilsglniagmsiknlhtdidtvfikdmckdvhkkvtesaye
iiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngi
sevfkpkltveeeqqlknsaetiwntqkdiql

    Sequence, based on observed residues (ATOM records): (download) 
    >6k12A (A:)
nkitvigvgavgmacafsilnkeladelvlidvvedklkgemmdlqqgslflktiiagkd
yeltansklvvvtagarqqegesrlnlvqrnvnifkfiipnvvkyspdcillivsnpvdi
ltyvawklsgfplnrvigsgcnldsarfrylvsemigihpsnfhgcilgehgdssvpils
glniagmsiknckdvhkkvtesayeiiklkgytswaiglsvgdlscsliknlrkvhpvst
lvkgqfgidnevflsvpcvlgrngisevfkpkltveeeqqlknsaetiwntqkdiql

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6k12B (B:)
mhslkeeflirltnedlnasnkitvigvgavgmacafsilnkeladelvlidvvedklkg
emmdlqqgslflktpniiagkdyeltansklvvvtagarqqegesrlnlvqrnvnifkfi
ipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnldsarfrylvsemigi
hpsnfhgcilgehgdssvpilsglniagmsiknlhtdidtvfikdmckdvhkkvtesaye
iiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngi
sevfkpkltveeeqqlknsaetiwntqkdiql

    Sequence, based on observed residues (ATOM records): (download) 
    >6k12B (B:)
nkitvigvgavgmacafsilnkeladelvlivvedklkgemmdlqqgslfliiagkdyel
tansklvvvtagvqrnvnifkfiipnvvkyspdcillivsnpvdiltyvawklsgfplnr
vigsgcnldsarfrylvsemigihpsnfhgcilgehgdssvpilsglniagmsdvhkkvt
esayeiiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvl
grngisevfkpkltveeeqqlknsaetiwntqkdiql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6k12C (C:)
mhslkeeflirltnedlnasnkitvigvgavgmacafsilnkeladelvlidvvedklkg
emmdlqqgslflktpniiagkdyeltansklvvvtagarqqegesrlnlvqrnvnifkfi
ipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnldsarfrylvsemigi
hpsnfhgcilgehgdssvpilsglniagmsiknlhtdidtvfikdmckdvhkkvtesaye
iiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngi
sevfkpkltveeeqqlknsaetiwntqkdiql

    Sequence, based on observed residues (ATOM records): (download) 
    >6k12C (C:)
nkitvigvgavgmacafsilnkeladelvlivvedklkgemmdlqqgslflktiiagkdy
eltansklvvvtagvqrnvnifkfiipnvvkyspdcillivsnpvdiltyvawklsgfpl
nrvigsgcnldsarfrylvsemigihpsnfhgcilgehgdssvpilsglniagmsckdvh
kkvtesayeiiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsv
pcvlgngisevfkpkltveeeqqlknsaetiwntqkdiql

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6k12D (D:)
mhslkeeflirltnedlnasnkitvigvgavgmacafsilnkeladelvlidvvedklkg
emmdlqqgslflktpniiagkdyeltansklvvvtagarqqegesrlnlvqrnvnifkfi
ipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnldsarfrylvsemigi
hpsnfhgcilgehgdssvpilsglniagmsiknlhtdidtvfikdmckdvhkkvtesaye
iiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngi
sevfkpkltveeeqqlknsaetiwntqkdiql

    Sequence, based on observed residues (ATOM records): (download) 
    >6k12D (D:)
nkitvigavgmacafsilnkeladelvlidvvedklkgemmdlqqgslflniiagkdyel
tansklvvvtfkfiipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnld
sarfrylvsemigihpsnfhgcilgehgdssvpilsglniagmshkkvtesayeiilkgy
tswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngisevfkpk
ltveeeqqlknsaetiwntqkdiql

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6k12F (F:)
mhslkeeflirltnedlnasnkitvigvgavgmacafsilnkeladelvlidvvedklkg
emmdlqqgslflktpniiagkdyeltansklvvvtagarqqegesrlnlvqrnvnifkfi
ipnvvkyspdcillivsnpvdiltyvawklsgfplnrvigsgcnldsarfrylvsemigi
hpsnfhgcilgehgdssvpilsglniagmsiknlhtdidtvfikdmckdvhkkvtesaye
iiklkgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngi
sevfkpkltveeeqqlknsaetiwntqkdiql

    Sequence, based on observed residues (ATOM records): (download) 
    >6k12F (F:)
nkitvigvgavgmacafsilnkeladelvlidvvedklkemmdlqqgslflktpniiagk
eltansklvvvtagiipnvvkyspcillivsnpvdiltyvawklsgfplnrvigsgcnld
sarfrylvsemigihpsnfhgcilgehgdssvpilsglniagmsdvhkkvtesayeiikl
kgytswaiglsvgdlscsliknlrkvhpvstlvkgqfgidnevflsvpcvlgrngisevf
kkltveeeqqlknsaetitqkdiql