PDB entry 6jz0

View 6jz0 on RCSB PDB site
Description: Crystal structure of EGFR kinase domain in complex with compound 78
Class: transferase/inhibitor
Keywords: kinase, ATP binding site, covalent bonding with ligand, TRANSFERASE-INHIBITOR complex
Deposited on 2019-04-30, released 2019-12-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 2.86 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Epidermal growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EGFR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6jz0a_
  • Heterogens: CKO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jz0A (A:)
geapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspka
nkeildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyll
nwcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggk
vpikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpq
ppictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptds
nfyralmdeedmddvvdadeylipqq

    Sequence, based on observed residues (ATOM records): (download) 
    >6jz0A (A:)
geapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelratspkan
keildeayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqylln
wcvqiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkv
pikwmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqp
pictidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlmdeedmd
dvvdadeylip