PDB entry 6fbo

View 6fbo on RCSB PDB site
Description: Human Methionine Adenosyltransferase II mutant (S114A) in I222 crystal form
Class: transferase
Keywords: transferase
Deposited on 2017-12-19, released 2019-01-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31153 (Start-394)
      • engineered mutation (113)
    Domains in SCOPe 2.07: d6fboa1, d6fboa2, d6fboa3
  • Heterogens: ADN, K, MG, PPK, PG4, PEG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fboA (A:)
mngqlngfheafieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetva
ktgmillageitsraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqg
vhldrneedigagdqglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpds
ktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedt
iyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarw
vakslvkgglcrrvlvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvi
vrdldlkkpiyqrtaayghfgrdsfpwevpkklky

    Sequence, based on observed residues (ATOM records): (download) 
    >6fboA (A:)
egtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsr
aavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqapdiaqgvhldrneedigagd
qglmfgyatdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrga
vlpirvhtivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfvigg
pqgdagltgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrv
lvqvsyaigvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrt
aayghfgrdsfpwevpkklky