PDB entry 6f28

View 6f28 on RCSB PDB site
Description: Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with (S)-1-[2'-Amino-2'-carboxyethyl]-6-methyl-5,7-dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 2.4A
Class: membrane protein
Keywords: ionotropic glutamate receptor, GluK3, ligand binding domain, membrane protein., MEMBRANE PROTEIN
Deposited on 2017-11-23, released 2018-02-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-21, with a file datestamp of 2018-03-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, kainate 3,Glutamate receptor ionotropic, kainate 3
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grik3, Glur7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42264 (Start-117)
      • linker (118-119)
    • Uniprot P42264 (120-257)
    Domains in SCOPe 2.08: d6f28a_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, kainate 3,Glutamate receptor ionotropic, kainate 3
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grik3, Glur7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42264 (Start-117)
      • linker (118-119)
    • Uniprot P42264 (120-End)
    Domains in SCOPe 2.08: d6f28b_
  • Heterogens: ZN, CG8, CL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6f28A (A:)
gpgtnrslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlved
gkygaqddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgt
pidsaddlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqr
tltadyallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqe
edklhimkekwwrgsgcp

    Sequence, based on observed residues (ATOM records): (download) 
    >6f28A (A:)
nrslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlvedgkyg
aqddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgtpids
addlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqrtlta
dyallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqeedkl
himkekwwrgsgcp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6f28B (B:)
gpgtnrslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlved
gkygaqddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgt
pidsaddlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqr
tltadyallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqe
edklhimkekwwrgsgcp

    Sequence, based on observed residues (ATOM records): (download) 
    >6f28B (B:)
rslivttlleepfvmfrksdrtlygndrfegycidllkelahilgfsyeirlvedgkyga
qddkgqwngmvkelidhkadlavapltithvrekaidfskpfmtlgvsilyrkgtpidsa
ddlakqtkieygavkdgatmtffkkskistfekmwafmsskpsalvknneegiqrtltad
yallmesttieyitqrncnltqigglidskgygigtpmgspyrdkitiailqlqeedklh
imkekwwrgsgc