PDB entry 6azz

View 6azz on RCSB PDB site
Description: Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
Class: immune system
Keywords: Transmission blocking vaccine, malaria, antibody, EGF-like domain, IMMUNE SYSTEM
Deposited on 2017-09-13, released 2017-11-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pfs25
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ
  • Chain 'B':
    Compound: 1190 antibody, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ (0-End)
    Domains in SCOPe 2.07: d6azzb1, d6azzb2
  • Chain 'C':
    Compound: 1190 antibody, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ (0-End)
  • Chain 'D':
    Compound: Pfs25
    Species: Plasmodium falciparum [TaxId:5833]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ
  • Chain 'E':
    Compound: 1190 antibody, light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ (0-End)
    Domains in SCOPe 2.07: d6azze1, d6azze2
  • Chain 'F':
    Compound: 1190 antibody, heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6AZZ (0-End)
  • Heterogens: ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6azzB (B:)
syvltqppsvsvapgqtaritcggsnigsksvhwyqqkpgqtpmlviyydydrpsgiper
fsgsnsgstatltisrveagdeadyycqvwdsssdhvwvfgggttltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6azzB (B:)
syvltqppsvsvapgqtaritcggsnigsksvhwyqqkpgqtpmlviyydydrpsgiper
fsgsnsgstatltisrveagdeadyycqvwdsssdhvwvfgggttltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6azzE (E:)
syvltqppsvsvapgqtaritcggsnigsksvhwyqqkpgqtpmlviyydydrpsgiper
fsgsnsgstatltisrveagdeadyycqvwdsssdhvwvfgggttltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6azzE (E:)
syvltqppsvsvapgqtaritcggsnigsksvhwyqqkpgqtpmlviyydydrpsgiper
fsgsnsgstatltisrveagdeadyycqvwdsssdhvwvfgggttltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'F':
    No sequence available.