PDB entry 6apv

View 6apv on RCSB PDB site
Description: Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic acid
Class: transferase
Keywords: Trypanosoma brucei, Purine salvage, acyclic nucleoside biphosphonate, TRANSFERASE
Deposited on 2017-08-18, released 2018-03-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: HGPRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6apva_
  • Chain 'B':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: HGPRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6apvb_
  • Chain 'C':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: HGPRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6apvc_
  • Chain 'D':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: HGPRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6apvd_
  • Heterogens: 3L4, MG, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6apvA (A:)
hhhhhhmepackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlk
gsfvftadmvrilgdfgvptrveflrassyghdtkscgrvdvkadglcdirgkhvlvled
ildtaltlrevvdslkksepasiktlvaidkpggrkipftaeyvvadvpnvfvvgygldy
dqsyrevrdvvilkpsvyetwgkelerrkaageakr

    Sequence, based on observed residues (ATOM records): (download) 
    >6apvA (A:)
ckydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadmv
rilgdfgvptrveflradirgkhvlvledildtaltlrevvdslkksepasiktlvaidk
pggrkipftaeyvvadvpnvfvvgygldydqsyrevrdvvilkpsvyetwgkele

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6apvB (B:)
hhhhhhmepackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlk
gsfvftadmvrilgdfgvptrveflrassyghdtkscgrvdvkadglcdirgkhvlvled
ildtaltlrevvdslkksepasiktlvaidkpggrkipftaeyvvadvpnvfvvgygldy
dqsyrevrdvvilkpsvyetwgkelerrkaageakr

    Sequence, based on observed residues (ATOM records): (download) 
    >6apvB (B:)
ckydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadmv
rilgdfgvptrveflrassydirgkhvlvledildtaltlrevvdslkksepasiktlva
idkpggrkipftaeyvvadvpnvfvvgygldydqsyrevrdvvilkpsvyetwgkelerr
kaa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6apvC (C:)
hhhhhhmepackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlk
gsfvftadmvrilgdfgvptrveflrassyghdtkscgrvdvkadglcdirgkhvlvled
ildtaltlrevvdslkksepasiktlvaidkpggrkipftaeyvvadvpnvfvvgygldy
dqsyrevrdvvilkpsvyetwgkelerrkaageakr

    Sequence, based on observed residues (ATOM records): (download) 
    >6apvC (C:)
ckydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadmv
rilgdfgvptrveflradirgkhvlvledildtaltlrevvdslkksepasiktlvaidk
pggrkipftaeyvvadvpnvfvvgygldydqsyrevrdvvilkpsvyetwgkel

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6apvD (D:)
hhhhhhmepackydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlk
gsfvftadmvrilgdfgvptrveflrassyghdtkscgrvdvkadglcdirgkhvlvled
ildtaltlrevvdslkksepasiktlvaidkpggrkipftaeyvvadvpnvfvvgygldy
dqsyrevrdvvilkpsvyetwgkelerrkaageakr

    Sequence, based on observed residues (ATOM records): (download) 
    >6apvD (D:)
ckydfatsvlfteaelhtrmrgvaqriaddysncnlkplenplvivsvlkgsfvftadmv
rilgdfgvptrveflradirgkhvlvledildtaltlrevvdslkksepasiktlvaidk
pggrkipftaeyvvadvpnvfvvgygldydqsyrevrdvvilkpsvyetwgkeler