PDB entry 5xu8

View 5xu8 on RCSB PDB site
Description: Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine
Class: hydrolase
Keywords: Ternary complex, ESI complex, HYDROLASE
Deposited on 2017-06-22, released 2018-02-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: USP2, UBP41
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xu8a_
  • Chain 'B':
    Compound: Ubiquitin-40S ribosomal protein S27a
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xu8b_
  • Heterogens: DX4, ZN, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xu8A (A:)
mnsksaqglaglrnlgntcfmnsilqclsntrelrdyclqrlymrdlhhgsnahtalvee
fakliqtiwtsspndvvspsefktqiqryaprfvgynqqdaqeflrflldglhnevnrvt
lrpksnpenldhlpddekgrqmwrkyleredsrigdlfvgqlkssltctdcgycstvfdp
fwdlslpiakrgypevtlmdcmrlftkedvldgdekptccrcrgrkrcikkfsiqrfpki
lvlhlkrfsesrirtsklttfvnfplrdldlrefasentnhavynlyavsnhsgttmggh
ytaycrspgtgewhtfndssvtpmsssqvrtsdayllfyelasppsrmlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5xu8A (A:)
qglaglrnlgntcfmnsilqclsntrelrdyclqrlymrdlhhgsnahtalveefakliq
tiwtsspndvvspsefktqiqryaprfvgynqqdaqeflrflldglhnevnrvnldhlpd
dekgrqmwrkyleredsrigdlfvgqlkssltctdcgycstvfdpfwdlslpiakrgype
vtlmdcmrlftkedvldgdekptccrcrgrkrcikkfsiqrfpkilvlhlkrfsesrirt
sklttfvnfplrdldlrefasentnhavynlyavsnhsgttmgghytaycrspgtgewht
fndssvtpmsssqvrtsdayllfyela

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5xu8B (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg