PDB entry 5wew

View 5wew on RCSB PDB site
Description: Crystal structure of Klebsiella pneumoniae fosfomycin resistance protein (FosAKP) with inhibitor (ANY1) bound
Class: transferase/transferase inhibitor
Keywords: fosfomycin, FosA, FosAKP, glutathione S-transferase, ANY1, TRANSFERASE, transferase-transferase inhibitor complex
Deposited on 2017-07-10, released 2018-07-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-07-18, with a file datestamp of 2018-07-13.
Experiment type: XRAY
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed):
    • Uniprot W8UNW6 (0-138)
      • expression tag (139)
    Domains in SCOPe 2.07: d5wewa1, d5wewa2
  • Chain 'B':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed):
    • Uniprot W8UNW6 (0-138)
      • expression tag (139-140)
    Domains in SCOPe 2.07: d5wewb1, d5wewb2
  • Chain 'C':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wewc_
  • Chain 'D':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wewd_
  • Chain 'E':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wewe_
  • Chain 'F':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wewf_
  • Chain 'G':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed):
    • Uniprot W8UNW6 (0-138)
      • expression tag (139-140)
    Domains in SCOPe 2.07: d5wewg1, d5wewg2
  • Chain 'H':
    Compound: Fosfomycin resistance protein
    Species: Klebsiella pneumoniae 30684/NJST258_2 [TaxId:1420013]
    Gene: KPNJ2_04803
    Database cross-references and differences (RAF-indexed):
    • Uniprot W8UNW6 (0-138)
      • expression tag (139-140)
    Domains in SCOPe 2.07: d5wewh1, d5wewh2
  • Heterogens: MN, A81

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wewA (A:)
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eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewA (A:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5wewB (B:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewB (B:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5wewC (C:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewC (C:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5wewD (D:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewD (D:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvff

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5wewE (E:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewE (E:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiswklnrsegashyfldpdghklelhvgslaqrlaacreqpykgmvff

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5wewF (F:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewF (F:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvff

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5wewG (G:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewG (G:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhh

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5wewH (H:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wewH (H:)
mlsglnhltlavsqlapsvafyqqllgmtlharwdsgaylscgdlwlclsldpqrrvtpp
eesdythyafsiseadfasfaarleaagvavwklnrsegashyfldpdghklelhvgsla
qrlaacreqpykgmvffeqhh