PDB entry 5vjp

View 5vjp on RCSB PDB site
Description: Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with L-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (L-DIAB) and Adenine
Class: transferase/transferase inhibitor
Keywords: Adenine phosphoribosyltransferase, Transition state analogue, L-2, 5-Dideoxy-2, 5-imino-altritol-1, 6-bisphosphate, L-DIAB, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-04-19, released 2017-12-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenine phosphoribosyltransferase 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: APT1, YML022W
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49435 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.07: d5vjpa1, d5vjpa2
  • Chain 'B':
    Compound: adenine phosphoribosyltransferase 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: APT1, YML022W
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49435 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.07: d5vjpb1, d5vjpb2
  • Heterogens: IR9, EDO, ADE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5vjpA (A:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaip
agsnviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftllna
qkealkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5vjpA (A:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatylfeiqknaipagsnvii
vddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftlln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5vjpB (B:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaip
agsnviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftllna
qkealkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5vjpB (B:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaip
agsnviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftlln