PDB entry 5tkm

View 5tkm on RCSB PDB site
Description: Crystal structure of human APOBEC3B N-terminal Domain
Class: hydrolase
Keywords: hydrolase, deaminase, apobec
Deposited on 2016-10-07, released 2017-06-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA dC->dU-editing enzyme APOBEC-3B
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UH17
      • engineered mutation (19)
      • engineered mutation (34)
      • engineered mutation (89)
      • engineered mutation (133)
      • engineered mutation (152)
      • engineered mutation (168)
    Domains in SCOPe 2.07: d5tkma_
  • Chain 'B':
    Compound: DNA dC->dU-editing enzyme APOBEC-3B
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UH17
      • engineered mutation (19)
      • engineered mutation (34)
      • engineered mutation (89)
      • engineered mutation (133)
      • engineered mutation (152)
      • engineered mutation (168)
    Domains in SCOPe 2.07: d5tkmb_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tkmA (A:)
gpggsggmnpqirnpmermdrdtfydnfenepilsgrsytwlcyevkikrgrsnllwdtg
vfrgqvyfkpqyhaemcflswfcgnqlpadkcfqitwfvswtpcpdcvaklaeflsehpn
vtltisaarlyyyserdyrralcrlsqagarvkimdyeefaycwenfvdnegqqfmpwyk
fdenyaflhrtlkeilrh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tkmA (A:)
npmermdrdtfydnfenepilsgrsytwlcyevkikrgrsnllwdtgvfrgqvyfkpqyh
aemcflswfcgnqlpadkcfqitwfvswtpcpdcvaklaeflsehpnvtltisaarlyyy
serdyrralcrlsqagarvkimdyeefaycwenfvdnegqqfmpwykfdenyaflhrtlk
eilr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5tkmB (B:)
gpggsggmnpqirnpmermdrdtfydnfenepilsgrsytwlcyevkikrgrsnllwdtg
vfrgqvyfkpqyhaemcflswfcgnqlpadkcfqitwfvswtpcpdcvaklaeflsehpn
vtltisaarlyyyserdyrralcrlsqagarvkimdyeefaycwenfvdnegqqfmpwyk
fdenyaflhrtlkeilrh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tkmB (B:)
npmermdrdtfydnfenepilsgrsytwlcyevkikrgrsnllwdtgvfrgqvyfkpqyh
aemcflswfcgnqlpadkcfqitwfvswtpcpdcvaklaeflsehpnvtltisaarlyyy
serdyrralcrlsqagarvkimdyeefaycwenfvdnegqqfmpwykfdenyaflhrtlk
eilr