PDB entry 5t4z

View 5t4z on RCSB PDB site
Description: structure of the anti-hiv antibody dh501 that binds gp120 v3 glycan and the base of v3 with free man9 glycan
Class: immune system
Keywords: HIV-1 antibody gp120, IMMUNE SYSTEM
Deposited on 2016-08-30, released 2017-03-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody DH501 Fab heavy chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5T4Z (0-End)
    Domains in SCOPe 2.08: d5t4za_
  • Chain 'B':
    Compound: antibody DH501 Fab light chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5T4Z
    Domains in SCOPe 2.08: d5t4zb1, d5t4zb2
  • Chain 'H':
    Compound: antibody DH501 Fab heavy chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5T4Z (0-229)
    Domains in SCOPe 2.08: d5t4zh_
  • Chain 'L':
    Compound: antibody DH501 Fab light chain
    Species: Macaca mulatta [TaxId:9544]
    Database cross-references and differences (RAF-indexed):
    • PDB 5T4Z
    Domains in SCOPe 2.08: d5t4zl1, d5t4zl2
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5t4zA (A:)
qvtlkefgpalvkptqpltltcsfsgfslrssdtavvwirqppgkalewlaaiywddveh
inpslksrlsiskdspnslvvltmanmdpvdtatyycgrvrfvsggyytdridswgpgll
vtvssastkgpsvfplapssrstsestaalgclvkdyfpepvtvswnsgsltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyvcnvnhkpsntkvdkrveiktcgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5t4zA (A:)
qvtlkefgpalvkptqpltltcsfsgfslrssdtavvwirqppgkalewlaaiywddveh
inpslksrlsiskdspnslvvltmanmdpvdtatyycgrvrfvsggyytdridswgpgll
vtvssastkgpsvfplapestaalgclvkdyfpepvtvswnsgsltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyvcnvnhkpsntkvdkrve

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5t4zB (B:)
qsvltqppsvsgapgqrvtiscagtksnigdcsvswyqqlpgatprlliyqnnnrpsgvs
drfsgsksgtsaslaitglqtedeadyfclsydtsfsgwrfgggtrltvlgqpkasptvt
lfppsseelqankatlvclisdfypgvvkvawkadgsavnagvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvapaecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5t4zB (B:)
vltqppsvsgapgqrvtiscagtksnigdcsvswyqqlpgatprlliyqnnnrpsgvsdr
fsgsksgtsaslaitglqtedeadyfclsydtsfsgwrfgggtrltvlgqpkasptvtlf
ppsseelqankatlvclisdfypgvvkvawkadgsavnagvetttpskqsnnkyaassyl
sltsdqwkshksyscqvthegstvektvap

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5t4zH (H:)
qvtlkefgpalvkptqpltltcsfsgfslrssdtavvwirqppgkalewlaaiywddveh
inpslksrlsiskdspnslvvltmanmdpvdtatyycgrvrfvsggyytdridswgpgll
vtvssastkgpsvfplapssrstsestaalgclvkdyfpepvtvswnsgsltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyvcnvnhkpsntkvdkrveiktcgg

    Sequence, based on observed residues (ATOM records): (download) 
    >5t4zH (H:)
qvtlkefgpalvkptqpltltcsfsgfslrssdtavvwirqppgkalewlaaiywddveh
inpslksrlsiskdspnslvvltmanmdpvdtatyycgrvrfvsggyytdridswgpgll
vtvssastkgpsvfplapstsestaalgclvkdyfpepvtvswnsgsltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyvcnvnhkpsntkvdkrveiktcgg

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5t4zL (L:)
qsvltqppsvsgapgqrvtiscagtksnigdcsvswyqqlpgatprlliyqnnnrpsgvs
drfsgsksgtsaslaitglqtedeadyfclsydtsfsgwrfgggtrltvlgqpkasptvt
lfppsseelqankatlvclisdfypgvvkvawkadgsavnagvetttpskqsnnkyaass
ylsltsdqwkshksyscqvthegstvektvapaecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5t4zL (L:)
vltqppsvsgapgqrvtiscagtksnigdcsvswyqqlpgatprlliyqnnnrpsgvsdr
fsgsksgtsaslaitglqtedeadyfclsydtsfsgwrfgggtrltvlgqpkasptvtlf
ppsseelqankatlvclisdfypgvvkvawkadgsavnagvetttpskqsnnkyaassyl
sltsdqwkshksyscqvthegstvektvapaec