PDB entry 5m6u

View 5m6u on RCSB PDB site
Description: human pi3kdelta in complex with lasw1579
Class: transferase
Keywords: PI3KDELTA KINASE, PROTEROS BIOSTRUCTURES GMBH, transferase
Deposited on 2016-10-26, released 2017-02-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-02-01, with a file datestamp of 2017-01-26.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: Pik3cd
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Phosphatidylinositol 3-kinase regulatory subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3R1, GRB1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27986
      • conflict (468)
      • conflict (518)
      • conflict (528)
      • conflict (538)
    Domains in SCOPe 2.07: d5m6ub_
  • Heterogens: 7KA

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5m6uB (B:)
msaegyqyralydykkereedidlhlgdiltvnkgslvalgfsdgqearpeeigwlngyn
ettgergdfpgtyveyigrkkispptpkprpprplpvapgsskteadveqqaltlpdlae
qfappdiapplliklveaiekkglecstlyrtqsssnlaelrqlldcdtpsvdlemidvh
vladafkrylldlpnpvipaavysemislapevqsseeyiqllkklirspsiphqywltl
qyllkhffklsqtssknllnarvlseifspmlfrfsaassdntenlikvieilistewne
rqpapalppkppkpttvanngmnnnmslqdaewywgdisreevneklrdtadgtflvrda
stkmhgdytltlrkggnnklikifhrdgkygfsdpltfssvvelinhyrneslaqynpkl
dvkllypvskyqqdqvvkednieavgkklheyntqfqeksreydrlyedytrtsqeiqmk
rtaieafnetikifeeqcqtqeryskeyiekfkregneteiqrimhnyeklksriseivd
srrrleedlkkqaaeyreidkrmnsikpdliqlrktrdqylmwltqkgvrqkklnewlgn
entedqyslveddedlphhdektwnvgssnrnkaenllrgkrdgtflvresskqgcyacs
vvvdgevkhcvinktatgygfaepynlysslkelvlhyqhtslvqhndslnvtlaypvya
qqrr

    Sequence, based on observed residues (ATOM records): (download) 
    >5m6uB (B:)
vvkednieavgkklheyntqfqeksreydrlyedytrtsqeiqmkrtaieafnetikife
eqcqtqeryskeyiekfkregneteiqrimhnyeklksriseivdsrrrleedlkkqaae
yreidkrmnsikpdliqlrktrdqylmwltqkgvrqkklnewlg