PDB entry 5lpt

View 5lpt on RCSB PDB site
Description: tRNA guanine Transglycosylase (TGT) in co-crystallized complex (space group P21) with 6-amino-2-(methylamino)-4-(2-((2R,3R,4S,5R,6S)-3,4,5,6-tetramethoxytetrahydro-2H-pyran-2-yl)ethyl)-1H-imidazo[4,5-g]quinazolin-8(7H)-one
Class: transferase
Keywords: Carbohydrate-based Inhibitors, homodimer, shigellosis, TRANSFERASE, TRANSFERASE INHIBITOR
Deposited on 2016-08-14, released 2017-08-30
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-08-30, with a file datestamp of 2017-08-25.
Experiment type: XRAY
Resolution: 2.36 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720 (Start-385)
      • conflict (311)
    Domains in SCOPe 2.06: d5lpta_
  • Chain 'B':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720 (Start-385)
      • conflict (311)
    Domains in SCOPe 2.06: d5lptb_
  • Heterogens: ZN, 726, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5lptA (A:)
mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqsee
gvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrwak
rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdem
frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
irdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >5lptA (A:)
drprfsfsiaaregkartgtiemkrgvirtpafmpvgtaagadiilgntyhlmlrpgaer
iaklgglhsfmgwdrpiltdsggyqvmslssltkqseegvtfkshldgsrhmlspersie
iqhllgsdivmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaalfgiq
qgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphylmgv
gkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsechcav
cqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryf
arns

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5lptB (B:)
mveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpetvr
atgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqsee
gvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrwak
rsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqdem
frvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpi
nirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlmqk
irdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >5lptB (B:)
drprfsfsiaaregkartgtiemkrgvirtpafmpvgtaaratgadiilgntyhlmlrpg
aeriaklgglhsfmgwdrpiltdsggyqvmslssltkqseegvtfkshldgsrhmlsper
sieiqhllgsdivmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaalf
giqqgsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphyl
mgvgkpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsech
cavcqkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfra
ryfarns