PDB entry 5jfe

View 5jfe on RCSB PDB site
Description: Flavin-dependent thymidylate synthase with H2-dUMP
Class: transferase
Keywords: thymidylate synthase, complex, H2-dUMP ligand, TRANSFERASE
Deposited on 2016-04-19, released 2017-04-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-04-26, with a file datestamp of 2017-04-21.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase thyX
    Species: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [TaxId:243274]
    Gene: thyX, thy1, TM_0449
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9WYT0 (12-End)
      • expression tag (11)
    Domains in SCOPe 2.06: d5jfea1, d5jfea2
  • Heterogens: FAD, UMC, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5jfeA (A:)
mgsdkihhhhhhmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieyl
mkhghetpfehivftfhvkapifvarqwfrhriasynelsgrysklsyefyipsperleg
ykttippervtekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslm
nflnlradshaqweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

    Sequence, based on observed residues (ATOM records): (download) 
    >5jfeA (A:)
hmkidildkgfvelvdvmgndlsavraarvsfdmeerdrhlieylmkhghetpfehivft
fhvkapifvarqwfrhriasynelsgrysklsyefyipsperlegykttippervtekis
eivdkayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqwei
qqyalaiarifkekcpwtfeaflkyaykgdilk