PDB entry 5ipa

View 5ipa on RCSB PDB site
Description: Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with (E)-3-(furan-3-yl)-1-(pyrrolidin-1-yl)prop-2-en-1-one at 1.78A resolution
Class: transcription
Keywords: EthR, transcription, represor, boosting effect
Deposited on 2016-03-09, released 2017-03-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TetR-family transcriptional regulatory repressor protein
    Species: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) [TaxId:419947]
    Gene: ethR, MRA_3895
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ipaa1, d5ipaa2
  • Heterogens: 6C8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ipaA (A:)
mttsaasqaslprgrrtarpsgddrelailataenlledrpladisvddlakgagisrpt
fyfyfpskeavlltlldrvvnqadmalqtlaenpadtdrenmwrtginvffetfgshkav
tragqaaratsvevaelwstfmqkwiaytaavidaerdrgaaprtlpahelatalnlmne
rtlfasfageqpsvpearvldtlvhiwvtsiygenr

    Sequence, based on observed residues (ATOM records): (download) 
    >5ipaA (A:)
gddrelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvn
qadmalqtlaenpadtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstf
mqkwiaytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvld
tlvhiwvtsiyge