PDB entry 5i7a

View 5i7a on RCSB PDB site
Description: Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 1 [3-(3-(3,4-Dichlorophenyl)ureido)benzoic acid]
Class: lyase
Keywords: Mycobacterium tuberculosis, Cysteine biosynthesis, sulphur metabolism, inhibitor, transferase, lyase
Deposited on 2016-02-17, released 2016-08-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-08-17, with a file datestamp of 2016-08-12.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: O-phosphoserine sulfhydrylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cysM, MT1377
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5i7aa_
  • Chain 'B':
    Compound: O-phosphoserine sulfhydrylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cysM, MT1377
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5i7ab_
  • Chain 'C':
    Compound: O-phosphoserine sulfhydrylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cysM, MT1377
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5i7ac_
  • Chain 'D':
    Compound: O-phosphoserine sulfhydrylase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cysM, MT1377
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 68Q, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5i7aA (A:)
gshmarydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavr
mieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyg
aqiifsaaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeit
hfvaglgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeilt
arysvgavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadag
wkylstgayagslddaetalegqlwa

    Sequence, based on observed residues (ATOM records): (download) 
    >5i7aA (A:)
rydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavrmieqa
eadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelygaqiif
savatakelaatnpswvmlyqygnpantdshycgtgpelladlpeithfvaglgttgtlm
gtgrflrehvanvkivaaeprvpelydpeiltarysvgavdavrrtrelvhtegifagis
tgavlhaalgvgagalaageradialvvadagwkylstgay

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5i7aB (B:)
gshmarydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavr
mieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyg
aqiifsaaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeit
hfvaglgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeilt
arysvgavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadag
wkylstgayagslddaetalegqlwa

    Sequence, based on observed residues (ATOM records): (download) 
    >5i7aB (B:)
rydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavrmieqa
eadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelygaqiif
saaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeithfvag
lgttgtlmgtgrflrehvanvkivaaeprgfvpelydpeiltarysvgavdavrrtrelv
htegifagistgavlhaalgvgagalaageradialvvadagwkylstgaya

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5i7aC (C:)
gshmarydsllqalgntplvglqrlsprwddgrdgphvrlwakledrnptgsikdrpavr
mieqaeadgllrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelyg
aqiifsaaeggsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeit
hfvaglgttgtlmgtgrflrehvanvkivaaeprygegvyalrnmdegfvpelydpeilt
arysvgavdavrrtrelvhtegifagistgavlhaalgvgagalaageradialvvadag
wkylstgayagslddaetalegqlwa

    Sequence, based on observed residues (ATOM records): (download) 
    >5i7aC (C:)
rydsllqalgntplvglqrlsprwddhvrlwakledrnptgsikdrpavrmieqaeadgl
lrpgatileptsgntgislamaarlkgyrlicvmpentsverrqllelygaqiifsaaeg
gsntavatakelaatnpswvmlyqygnpantdshycgtgpelladlpeithfvaglgttg
tlmgtgrflrehvanvkivaaeprpelydpeiltarysvgavdavrrtrelvhtegifag
istgavlhaalgvgagalaageradialvvadagwkylstgay

  • Chain 'D':
    No sequence available.