PDB entry 5eam

View 5eam on RCSB PDB site
Description: Crystal structure of human WDR5 in complex with compound 9o
Class: Transcription/Transcription inhibitor
Keywords: WDR5, compound 9o, Structural Genomics, Structural Genomics Consortium, SGC, Transcription-Transcription inhibitor complex
Deposited on 2015-10-16, released 2015-11-04
The last revision prior to the SCOPe 2.05 freeze date was dated 2015-11-04, with a file datestamp of 2015-10-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d5eama_
  • Chain 'B':
    Compound: WD repeat-containing protein 5
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR5, BIG3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d5eamb_
  • Heterogens: 5MN, EDO, UNX, SO4, BTB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5eamA (A:)
gtqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfekt
isghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsn
livsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtas
gqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekyci
fanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaale
ndktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >5eamA (A:)
vkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5eamB (B:)
gtqskptpvkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfekt
isghklgisdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsn
livsgsfdesvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtas
gqclktlidddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekyci
fanfsvtggkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaale
ndktiklwksdc

    Sequence, based on observed residues (ATOM records): (download) 
    >5eamB (B:)
vkpnyalkftlaghtkavssvkfspngewlasssadklikiwgaydgkfektisghklgi
sdvawssdsnllvsasddktlkiwdvssgkclktlkghsnyvfccnfnpqsnlivsgsfd
esvriwdvktgkclktlpahsdpvsavhfnrdgslivsssydglcriwdtasgqclktli
dddnppvsfvkfspngkyilaatldntlklwdyskgkclktytghknekycifanfsvtg
gkwivsgsednlvyiwnlqtkeivqklqghtdvvistachpteniiasaalendktiklw
ksdc