PDB entry 5ea1

View 5ea1 on RCSB PDB site
Description: Crystal Structure of SMARCA4 bromodomain in complex with MPD
Class: transcription
Keywords: four helical bundle, transcription
Deposited on 2015-10-15, released 2016-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-03-30, with a file datestamp of 2016-03-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcription activator BRG1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea1a_
  • Chain 'B':
    Compound: Transcription activator BRG1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea1b_
  • Chain 'C':
    Compound: Transcription activator BRG1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ea1c_
  • Heterogens: MRD, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ea1A (A:)
smlspnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfk
kikerirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkieked
dsegeeseeeee

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea1A (A:)
spnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfkkik
erirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkie

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ea1B (B:)
smlspnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfk
kikerirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkieked
dsegeeseeeee

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea1B (B:)
lspnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfkki
kerirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkiekedds
egeeseee

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ea1C (C:)
smlspnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfk
kikerirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkieked
dsegeeseeeee

    Sequence, based on observed residues (ATOM records): (download) 
    >5ea1C (C:)
lspnppnltkkmkkivdavikykdsssgrqlsevfiqlpsrkelpeyyelirkpvdfkki
kerirnhkyrslndlekdvmllcqnaqtfnlegsliyedsivlqsvftsvrqkiekedd