PDB entry 5dc4

View 5dc4 on RCSB PDB site
Description: crystal structure of monobody as25/abl1 sh2 domain complex, crystal a
Class: protein binding
Keywords: engineered binding protein, antibody mimic, protein-protein complex, sh2 domain, tyrosine-protein kinase, protein binding
Deposited on 2015-08-23, released 2016-03-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase ABL1
    Species: Homo sapiens [TaxId:9606]
    Gene: ABL1, ABL, JTK7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5dc4a_
  • Chain 'B':
    Compound: AS25 monobody
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5DC4 (Start-94)
    Domains in SCOPe 2.07: d5dc4b_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5dc4A (A:)
gspsnyitpvnslekhswyhgpvsrnaaeyllssgingsflvresesspgqrsislryeg
rvyhyrintasdgklyvssesrfntlaelvhhhstvadglittlhypapkrnkptvygvs
pny

    Sequence, based on observed residues (ATOM records): (download) 
    >5dc4A (A:)
slekhswyhgpvsrnaaeyllssgingsflvresesspgqrsislryegrvyhyrintas
dgklyvssesrfntlaelvhhhstvadglittlhypapkr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5dc4B (B:)
ssvsdvptklevvaatptslliswdapavtvdyyvitygetggwsgyqefevpgskstat
isglspgvdytitvyaygypyvkynkspisinyrt

    Sequence, based on observed residues (ATOM records): (download) 
    >5dc4B (B:)
sdvptklevvaatptslliswdapavtvdyyvitygetggwsgyqefevpgskstatisg
lspgvdytitvyaygypyvkynkspisinyrt