PDB entry 5d9j

View 5d9j on RCSB PDB site
Description: 2009 H1N1 PA endonuclease mutant F105S in complex with L-742,001
Class: hydrolase/hydrolase inhibitor
Keywords: influenza, resistance, endonuclease inhibitor, viral protein, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2015-08-18, released 2016-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (0-49)
      • linker (50-52)
    • Uniprot C3W5S0 (53-176)
      • engineered mutation (85)
      • expression tag (177-178)
    Domains in SCOPe 2.08: d5d9ja1, d5d9ja2
  • Heterogens: MN, 0N8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5d9jA (A:)
medfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdggskhrfeii
egrdrimawtvvnsicnttgvekpkslpdlydykenrfieigvtrrevhiyylekankik
sekthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqseraaa
elalvpr

    Sequence, based on observed residues (ATOM records): (download) 
    >5d9jA (A:)
medfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdggskhrfeii
egrdrimawtvvnsicnttgvekpkslpdlydykenrfieigvtrrevhiyylekankik
sekthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqseraa