PDB entry 5cs5

View 5cs5 on RCSB PDB site
Description: The structure of the NK1 fragment of HGF/SF complexed with PIPES
Class: hormone
Keywords: HGF/SF, NK1 fragment, fragment based drug discovery, growth factor, cell cycle, hormone, new chemical entity
Deposited on 2015-07-23, released 2015-08-12
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-12, with a file datestamp of 2015-08-07.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hepatocyte growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: HGF, HPTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5cs5a1, d5cs5a2
  • Chain 'B':
    Compound: hepatocyte growth factor
    Species: Homo sapiens [TaxId:9606]
    Gene: HGF, HPTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5cs5b1, d5cs5b2
  • Heterogens: PIN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5cs5A (A:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve

    Sequence, based on observed residues (ATOM records): (download) 
    >5cs5A (A:)
tihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqcl
wfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmip
hehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcseve

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5cs5B (B:)
yvegqrkrrntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckaf
vfdkarkqclwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgi
kcqpwssmiphehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcs
eve

    Sequence, based on observed residues (ATOM records): (download) 
    >5cs5B (B:)
ntihefkksakttlikidpalkiktkkvntadqcanrctrnkglpftckafvfdkarkqc
lwfpfnsmssgvkkefghefdlyenkdyirnciigkgrsykgtvsitksgikcqpwssmi
phehsflpssyrgkdlqenycrnprgeeggpwcftsnpevryevcdipqcsev