PDB entry 5cph

View 5cph on RCSB PDB site
Description: Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
Class: isomerase/isomerase inhibitor
Keywords: DNA gyrase, GyrB, fragment-based screening, structure-based design, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2015-07-21, released 2016-02-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-02-17, with a file datestamp of 2016-02-12.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5cpha_
  • Chain 'B':
    Compound: DNA gyrase subunit b
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5cphb_
  • Heterogens: EVO, SO4, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5cphA (A:)
gsvtalsdvnntdnygagqiqvlegleavrkrpgmyigstserglhhlvweivdnsidea
lagyanqievviekdnwikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyv
hrnetiyhqaykkgvpqfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirel
aflnkgiqitlrderdeenvredsyhyeggik

    Sequence, based on observed residues (ATOM records): (download) 
    >5cphA (A:)
agqiqvlegleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdn
wikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvp
qfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderd
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  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5cphB (B:)
gsvtalsdvnntdnygagqiqvlegleavrkrpgmyigstserglhhlvweivdnsidea
lagyanqievviekdnwikvtdngrgipvdiqekmgrpaveviltssvvnalsqdlevyv
hrnetiyhqaykkgvpqfdlkevgttdktgtvirfkadgeiftettvynyetlqqrirel
aflnkgiqitlrderdeenvredsyhyeggik

    Sequence, based on observed residues (ATOM records): (download) 
    >5cphB (B:)
qvlegleavrkrpgmyigstserglhhlvweivdnsidealagyanqievviekdnwikv
tdngrgipvdiqgrpaveviltssvvnalsqdlevyvhrnetiyhqaykkgvpqfdlkev
gttdktgtvirfkadgeiftettvynyetlqqrirelaflnkgiqitlrderdeenvred
syhyeg