PDB entry 5c55

View 5c55 on RCSB PDB site
Description: Crystal structure of the Y138F mutant of C.glutamicum N-acetylneuraminic acid lyase in complex with pyruvate
Class: lyase
Keywords: Complex, Aldolase type TIM barrel, Schiff base intermediate, LYASE
Deposited on 2015-06-19, released 2016-06-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-06-22, with a file datestamp of 2016-06-17.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydrodipicolinate synthase/N-acetylneuraminate lyase
    Species: Corynebacterium glutamicum ATCC 13032 [TaxId:196627]
    Gene: Cgl2646
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NMD2
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5c55a_
  • Chain 'B':
    Compound: Dihydrodipicolinate synthase/N-acetylneuraminate lyase
    Species: Corynebacterium glutamicum ATCC 13032 [TaxId:196627]
    Gene: Cgl2646
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NMD2
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5c55b_
  • Heterogens: PYR, EDO, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5c55A (A:)
masatftgvippvmtplhadgsvdveslrklvdhlinggvdglfalgssgeaafltraqr
klalttiiehtagrvpvtagvietttarvielvedaleagaeglvatapfytrthdveie
ehfrkihaaapelplfafnipvsvhsnlnpvmlltlakdgvlagtkdssgndgairslie
arddaglteqfkiltgsettvdfaylagadgvvpglgnvdpaayaalaklcldgkwaeaa
alqkrinhlfhivfvgdtshmsgssaglggfktalahlgiiesnamavphqslsdeetar
ihaivdeflyta

    Sequence, based on observed residues (ATOM records): (download) 
    >5c55A (A:)
tftgvippvmtplhadgsvdveslrklvdhlinggvdglfalgssgeaafltraqrklal
ttiiehtagrvpvtagvietttarvielvedaleagaeglvatapfytrthdveieehfr
kihaaapelplfafnipvsvhsnlnpvmlltlakdgvlagtkdssgndgairslieardd
aglteqfkiltgsettvdfaylagadgvvpglgnvdpaayaalaklcldgkwaeaaalqk
rinhlfhivfvgdtshmsgssaglggfktalahlgiiesnamavphqslsdeetarihai
vdeflyt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5c55B (B:)
masatftgvippvmtplhadgsvdveslrklvdhlinggvdglfalgssgeaafltraqr
klalttiiehtagrvpvtagvietttarvielvedaleagaeglvatapfytrthdveie
ehfrkihaaapelplfafnipvsvhsnlnpvmlltlakdgvlagtkdssgndgairslie
arddaglteqfkiltgsettvdfaylagadgvvpglgnvdpaayaalaklcldgkwaeaa
alqkrinhlfhivfvgdtshmsgssaglggfktalahlgiiesnamavphqslsdeetar
ihaivdeflyta

    Sequence, based on observed residues (ATOM records): (download) 
    >5c55B (B:)
tftgvippvmtplhadgsvdveslrklvdhlinggvdglfalgssgeaafltraqrklal
ttiiehtagrvpvtagvietttarvielvedaleagaeglvatapfytrthdveieehfr
kihaaapelplfafnipvsvhsnlnpvmlltlakdgvlagtkdssgndgairslieardd
aglteqfkiltgsettvdfaylagadgvvpglgnvdpaayaalaklcldgkwaeaaalqk
rinhlfhivfvgdtshmsgssaglggfktalahlgiiesnamavphqslsdeetarihai
vdefly