PDB entry 5bv8

View 5bv8 on RCSB PDB site
Description: G1324S mutation in von Willebrand Factor A1 domain
Class: blood clotting
Keywords: von Willebrand Factor, Platelet adhesion, VWFA, BLOOD CLOTTING
Deposited on 2015-06-04, released 2015-12-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-30, with a file datestamp of 2015-12-24.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: von willebrand factor
    Species: Homo sapiens [TaxId:9606]
    Gene: VWF, F8VWF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04275 (Start-235)
      • engineered mutation (98)
      • expression tag (236-243)
    Domains in SCOPe 2.06: d5bv8a1, d5bv8a2
  • Heterogens: EDO, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5bv8A (A:)
mrgshhhhhhgsqepgglvvpptdapvspttlyvedisepplhdfycsrlldlvflldgs
srlseaefevlkafvvdmmerlrisqkwvrvavveyhdsshayiglkdrkrpselrrias
qvkyagsqvastsevlkytlfqifskidrpeasritlllmasqepqrmsrnfvryvqglk
kkkvivipvgigphanlkqirliekqapenkafvlssvdeleqqrdeivsylcdlapeap
pptlppkln

    Sequence, based on observed residues (ATOM records): (download) 
    >5bv8A (A:)
disepplhdfycsrlldlvflldgssrlseaefevlkafvvdmmerlrisqkwvrvavve
yhdsshayiglkdrkrpselrriasqvkyagsqvastsevlkytlfqifskidrpeasri
tlllmasqepqrmsrnfvryvqglkkkkvivipvgigphanlkqirliekqapenkafvl
ssvdeleqqrdeivsylcdlapeappptl