PDB entry 5b5o
View 5b5o on RCSB PDB site
Description: Crystal structure of the catalytic domain of MMP-13 complexed with N-phenyl-4-((4H-1,2,4-triazol-3-ylsulfanyl)methyl)-1,3-thiazol-2-amine
Class: hydrolase/hydrolase inhibitor
Keywords: MMP-13, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2016-05-13, released
2017-01-18
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-02-08, with a file datestamp of
2017-02-03.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.65
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: collagenase 3
Species: Homo sapiens [TaxId:9606]
Gene: MMP13
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5b5oa_ - Chain 'B':
Compound: collagenase 3
Species: Homo sapiens [TaxId:9606]
Gene: MMP13
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5b5ob_ - Heterogens: ZN, CA, NA, EDO, WMM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5b5oA (A:)
eynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn
Sequence, based on observed residues (ATOM records): (download)
>5b5oA (A:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgfmlpdddvqgiqslygpgdedp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5b5oB (B:)
eynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn
Sequence, based on observed residues (ATOM records): (download)
>5b5oB (B:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp